The Effect of tDCS on Motor Performance and Cortical Excitability

Cortical Excitability Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01740843
• Other study ID #: MECU2012-004
• Status: Completed
• Phase: N/A
• First received: November 26, 2012
• Last updated: February 24, 2014
• Start date: August 2012
• Est. completion date: June 2013

Study information

• Verified date: February 2014
• Source: Hasselt University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Belgium: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

In this study the effect of tDCS intensity on motor performance and corticospinal (CS) excitability is evaluated. The investigators expect that a positive relationship between current intensity and motor performance/CS excitability.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: June 2013
• Est. primary completion date: April 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 85 Years

Eligibility

Inclusion Criteria:

• Healthy subjects

Exclusion Criteria:

• Contraindications for tDCS/TMS

• TMS measurements have to be possible

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Cortical Excitability
• Motor Performance
• tDCS

Intervention

Device:
• transcranial direct current stimulation (tDCS) (NeuroConn DC-stimulator)
The anode is fixed on the primary cortex and the cathode will be fixed on the contralateral supraorbital region.

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Hasselt University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in motor performance	motor performance is assessed using different reaction time paradigms (simple reaction time, choice reaction time). This is done at baseline and immediately after the intervention (30 min after baseline)	Baseline and POST (30 min after baseline) intervention	No
Primary	Change in cortical excitability	Cortical excitability is measured using trancranial magnetic stimulation (TMS) measuring muscle evoked potentials (MEPs) at baseline and POST (30 min after baseline).	Baseline and POST (30 min after baseline) intervention	Yes