Corpus Callosum Agenesis Clinical Trial
Official title:
BECOME CHILDREN OF HOLDERS Corpus Callosum Agenesis Screened IN PERIOD Antenatal
The corpus callosum agenesis is an interesting malformation between 0.05% and 1.5% of the
general population. This malformation is mostly diagnosed prenatally by ultrasound, usually
at 22 weeks of gestation, and the use of prenatal advice is routinely offered to the couple.
Several studies in recent years have helped to define the determinants of prognosis for the
unborn child suffers from agenesis of the corpus callosum, whether total or partial. These,
mainly retrospective, demonstrated that the isolated nature of the deformity (defined as no
other brain malformations and brain extra, absence of abnormal karyotype, maternal poisoning
or viral seroconversion when pregnancy) is associated with favorable developments in terms
of psychomotor development in 80% of cases Similar results were also found in prospective
studies, while the associated nature of the defect seems most heavily encumber the prognosis
as other malformation or syndrome associated with agenesis of the corpus callosum Although
these recent data have already significantly influence prenatal counseling and outcome of
pregnancy, questions about the future of the child carrying a prenatal diagnosis of agenesis
of the corpus callosum are still valid.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05843110 -
Decision-making Process of Couples Confronted With Prenatal Diagnosis of an Isolated CCA
|
N/A |