Important Data on COVID-19 Profile in Africa

Coronavirus Infection Clinical Trial

— AIDCO  

Official title:

Important Data on COVID-19 Profile in Africa

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04847817
• Other study ID #: 0011/2020/PR/SG/CNE
• Secondary ID: CEI-10/2020
• Status: Completed
• Start date: August 1, 2020
• Est. completion date: March 1, 2022

Study information

• Verified date: April 2021
• Source: Centre de Recherche Médicale de Lambaréné
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to Understand the natural history of Coronavirus 2019 (COVID-19) infection to better define the period of infectiousness and transmissibility and to establish biobanks of COVID-19 blood and mucosal samples.

Description:

In this study ,the participants will be enrolled sequentially in the COVID-19 care referral centers. The infected hospitalized patient will be identified by the physicians in hospital. After the patient has given his/her informed consent the permission will be sought from him to approach his household contacts. The household contacts will be screened, and included in the study.

Patients hospitalized and positive for COVID-19 by PCR and their household contacts of all ages and gender (40% minimum of female), will be enrolled upon receipt of written informed consent.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 574
• Est. completion date: March 1, 2022
• Est. primary completion date: December 31, 2021
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Molecular (PCR) confirmed COVID-19 patients hospitalized in referral centers,

• Household contacts of hospitalized COVID-19 patient,

• Provided signed informed consent.

Exclusion Criteria:

• Pregnancy

Related Conditions & MeSH terms

• Africa
• Coronavirus Infection
• Coronavirus Infections
• COVID-19

Locations

Country	Name	City	State
Gabon	Centre de Recherches Médicales de Lambréné	Lambaréne
Gabon	Centre de Recherches Médicales de Lammbaréné	Lambaréné	Moyen- Ogooué

Sponsors (7)

Lead Sponsor	Collaborator
Centre de Recherche Médicale de Lambaréné	Armauer Hansen Research Institute, Ethiopia, European and Developing Countries Clinical Trials Partnership (EDCTP), Institut de recherche en santé de surveillance épidémiologique et de formation, Leiden University Medical Center, Universität Tübingen, Université des Sciences de la Santé

Country where clinical trial is conducted

Gabon, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	clinical and biological parameters of COVID-19	Infection and disease progression - Pattern of virus transmission	14 days
Primary	SARS-CoV-2 transmissibility	proportion of household contact who will become positive for SARS-COV2 using PCR	14 days