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Coronavirus Disease 2019 clinical trials

View clinical trials related to Coronavirus Disease 2019.

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NCT ID: NCT06163677 Withdrawn - COVID-19 Clinical Trials

A Study to Look at the Health Outcomes of Patients With COVID-19 and Influenza.

Start date: January 17, 2024
Phase:
Study type: Observational

The main purpose of this study is to understand: - the symptoms of COVID-19 or influenza - health-related outcomes of people with COVID-19 or influenza - the effects of vaccines in people with COVID-19 or influenza. This study will take in participants who are: - 18 years or older - reported to have symptoms with lab tests that have confirmed illness. The lab tests can be tested at any of Walgreens pharmacy COVID-19 or influenza test sites. The study will collect vaccine history information from participants who are ready to take part in the study. Participant will be emailed a form with questions about their health related to COVID-19 or influenza during twelve follow-ups over a 6-month period.

NCT ID: NCT05085574 Withdrawn - COVID-19 Clinical Trials

Leidos-Enabled Adaptive Protocol for Clinical Trials (LEAP-CT) in Hospitalized Patients With COVID-19 (Addendum 1)

Start date: February 7, 2023
Phase: Phase 2
Study type: Interventional

This study is designed to test the efficacy and safety of combinations of two well-understood agents - famotidine and celecoxib in patients hospitalized with moderate-to-severe COVID-19 (based on World Health Organization [WHO] Ordinal Scale for Clinical Improvement). Both famotidine and celecoxib separately demonstrate clinical activity in mitigating COVID-19 disease symptoms or severity, and appear to have separate and complementary mechanisms of action.

NCT ID: NCT04390217 Withdrawn - COVID-19 Clinical Trials

LB1148 for Pulmonary Dysfunction Associated With COVID-19 Pneumonia

Start date: October 31, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2, proof of concept, randomized, placebo-controlled, multicenter study to evaluate the ability of LB1148 to attenuate pulmonary dysfunction associated with COVID-19 pneumonia. The primary objective of this study is to determine if enteral administration of LB1148 will effect disease progression in hospitalized patients with moderate to severe COVID-19 via measurement of the proportion of subjects alive and free of respiratory failure at Day 28.

NCT ID: NCT04285190 Withdrawn - Clinical trials for Coronavirus Disease 2019

The Effect of T89 on Improving Oxygen Saturation and Clinical Symptoms in Patients With COVID-19

Start date: February 26, 2020
Phase: N/A
Study type: Interventional

This is an open-label, randomized, blank-controlled treatment clinical study. The objective of this study is to investigate the effect of T89 on improving oxygen saturation and clinical symptoms in patients with Coronavirus Disease 2019 (COVID-19). In this study, estimated total of 120-240 male and female patients who have been diagnosed with non-critical type of coronavirus pneumonia (COVID-19) will be enrolled and randomly assigned to one of two study groups, the T89 treatment group and the blank control group, to T89 or nothing on the base of a recommended standard treatment for up to 14 days . The primary efficacy parameters include the time to oxygen saturation recovery to normal level (≥97%), the proportion of patients with normal level of oxygen saturation after treatment, and the total duration of oxygen inhalation, oxygen flow change by time, oxygen concentration change by time during treatment.

NCT ID: NCT04283838 Withdrawn - Clinical trials for Coronavirus Disease 2019

Humanistic Care in Healthcare Workers in Coronavirus Disease 2019

Start date: February 22, 2020
Phase: N/A
Study type: Interventional

As of February 17th, 2020, China has 76396 confirmed cases of coronavirus disease 2019 (COVID-19), including 2348 deaths. The impact factors of clinical outcomes among hospitalized patients still need to be clarified. The healthcare workers faced greater mental and physical pressure under long-term, high-intensity, high-risk working conditions. Investigators aim to evaluate the positive effect of humanistic care for healthcare workers participated in the treatment of COVID-19.

NCT ID: NCT04283825 Withdrawn - Clinical trials for Coronavirus Disease 2019

Humanistic Care in Patients With Coronavirus Disease 2019

Start date: February 22, 2020
Phase: N/A
Study type: Interventional

As of February 17th, 2020, China has 76396 confirmed cases of coronavirus disease 2019 (COVID-19), including 2348 deaths. Although the impact factors of clinical outcomes among hospitalized patients still need to be clarified, some of the therapeutic regimens have shown the potency in the treatment of severe cases. Investigators aim to evaluate the efficacy of psychological and physical rehabilitation based humanistic care in the treatment of COVID-2019.

NCT ID: NCT04280913 Withdrawn - Clinical trials for Coronavirus Disease 2019

Clinical Outcomes of Patients With COVID19

Start date: February 22, 2020
Phase:
Study type: Observational

As of February 17th, 2020, China has 70635 confirmed cases of coronavirus disease 2019 (COVID-19), including 1772 deaths. Human-to-human spread of virus via respiratory droplets is currently considered to be the main route of transmission. The number of patients increased rapidly but the impact factors of clinical outcomes among hospitalized patients are still unclear.