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Clinical Trial Summary

The purpose of this study is to a) assess how coronavirus 2019 (COVID-19) affects cardiac function in middle age and older adults and b) assess if a physical activity intervention (increased daily step count by 2,000) can affect cardiac function in a population with a history of COVID-19.


Clinical Trial Description

Cardiac function will be assessed by obtaining arterial stiffness, comprehensive echocardiography measurements and haemodynamic monitoring. Arterial stiffness will assess primarily pulse wave velocity (PWV) and echocardiography. Graded cardiopulmonary exercise stress testing coupled with non-invasive gas exchange and haemodynamic monitoring will also be performed. Physical activity will be assessed objectively using pedometers and accelerometry. Quality of life, sleep/ circadian rhythm, fatigue, anxiety and depression will be measured using the validated Short-Form-36 (SF-36) questionnaire, Pittsburgh Sleep scale (PSQI), Chalder fatigue (CF) scale and the Depression, Anxiety and Stress Scale (DASS-21). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05492552
Study type Interventional
Source Coventry University
Contact
Status Completed
Phase N/A
Start date April 7, 2022
Completion date May 11, 2023

See also
  Status Clinical Trial Phase
Suspended NCT04371432 - Genetics of COVID-19 Susceptibility and Manifestations
Completed NCT04843917 - Immunity Against COVID-19 Vaccine in Healthcare Workers in Argentine