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Clinical Trial Summary

In this study, the investigators propose to investigate a novel technique for fluid responsiveness prediction. It is based on the occurrence of an extra systole, which induces a preload variation: Extra systoles are comprised by, first, the premature/ectopic beat with decreased cardiac preload, then, the post-ectopic beat with moderately increased preload.

Consequently, the post ectopic beat is associated with a Frank-Starling curve right shift but is otherwise a normal sinus beat. As such, the post-ectopic beat elucidates and predicts the hemodynamic effect of increasing preload, i.e. giving fluids

Clinical Trial Description


Study Design

Related Conditions & MeSH terms

NCT number NCT03002129
Study type Interventional
Source University Medical Center Groningen
Status Completed
Phase N/A
Start date January 2017
Completion date September 2017

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