The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

Corneal Transplantation Clinical Trial

Official title:

Trends in Corneal Transplantation From 2001 to 2016 in Germany: A Report of the DOG-Section Cornea and Its Keratoplasty Registry

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03381794
• Other study ID #: GKR01-16
• Status: Completed
• Phase: N/A
• First received: December 11, 2017
• Last updated: December 18, 2017
• Start date: January 1, 2001
• Est. completion date: December 31, 2016

Study information

• Verified date: December 2017
• Source: Saarland University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Aim of this study is to reflect on the changing trends in absolute numbers, surgical techniques and indications of corneal transplantations being performed in Germany.

In 2017, the Section Cornea of the German Ophthalmological Society provides an interim-assessment about the most up-to-date results of this long-term study over a period of sixteen years between 2001 and 2016.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 78165
• Est. completion date: December 31, 2016
• Est. primary completion date: December 31, 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 1 Year to 100 Years

Eligibility

Inclusion Criteria:

All patients in Germany treated with the different types of corneal transplantation from 2001 to 2016.

Exclusion Criteria:

Patients without corneal transplantation.

Related Conditions & MeSH terms

• Corneal Transplantation

Intervention

Procedure:
• Corneal transplantation
PKP: Penetrating Keratoplasty DALK: Deep Anterior Lamellar Keratoplasty DMEK: Descemet Membrane Endothelial Keratoplasty DSAEK: Descemet's Stripping Automated Endothelial Keratoplasty

Locations

Country	Name	City	State
Germany	Department of Ophthalmology	Homburg	Saarland

Sponsors (6)

Lead Sponsor	Collaborator
Saarland University	Charite University, Berlin, Germany, Heinrich-Heine University, Duesseldorf, University Eye Hospital, Freiburg, University of Cologne, University of Erlangen-Nürnberg

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	An overview about absolute numbers of corneal transplantation in Germany from 2001 to 2016.	A questionnaire about absolute numbers of corneal transplantation per year was sent to the 111 ophthalmological departments in Germany performing corneal transplantation. Data has been collected annually over a period of sixteen years in Germany between 2001 and 2016.	01/01/2001 to 31/12/2016
Primary	An overview about trends in the various types of corneal transplantation in Germany from 2001 to 2016.	The questionnaire also records the types of corneal transplantation (i.e. penetrating keratoplasty, deep anterior lamellar keratoplasty, Descemet membrane endothelial keratoplasty (DMEK) and Descemet's stripping automated endothelial keratoplasty DSAEK) allowing a discussion of trends in corneal transplantation. Data has been collected annually over a period of sixteen years in Germany between 2001 and 2016.	01/01/2001 to 31/12/2016
Primary	An overview about indications for corneal transplantation in Germany from 2001 to 2016.	The questionnaire also records the indications for corneal transplantation (e.g. Fuchs' endothelial corneal dystrophy, pseudophakic corneal decompensation, repeated keratoplasty after graft failure, keratoconus and corneal scarring). Data has been collected annually over a period of sixteen years in Germany between 2001 and 2016.	01/01/2001 to 31/12/2016