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Corneal Crosslinking in Keratoconus and Corneal Ectasia — CXL  

Corneal Ectasia Clinical Trial

Official title:
Corneal Collagen Cross-Linking for the Treatment of Progressive Keratoconus and Corneal Ectasia

Clinical Trial Summary

Prospective, randomized, single site to determine the safety and effectiveness of performing corneal collagen cross-linking (CXL) using riboflavin and UVA light in eyes progressive keratoconus or corneal ectasia.

Clinical Trial Description

After epithelial surface removal riboflavin drops are applied until there is saturation of the cornea.Then the UVA light is turned on to active the crosslinking process while drops are continued for the 30 minute of lamp use to replenish the riboflavin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00679666
Study type Interventional
Source Ohio State University
Contact
Status Withdrawn
Phase Phase 2/Phase 3
Start date April 2008
Completion date October 2010
View Details
See also
  Status Clinical Trial Phase
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Recruiting NCT04094090 - Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia Phase 2
Completed NCT04405882 - Cornea Ectasia Excimer Laser Treatment
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Recruiting NCT04401865 - Safety and Effectiveness of the PXL-Platinum 330 System Phase 1/Phase 2
Completed NCT05691335 - Three Different Cross-linking Protocols for Treatment of Pediatric Keratoconus N/A
Completed NCT04475900 - Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics
Recruiting NCT05027295 - Accelerated Corneal Collagen Crosslinking for Keratoconus and Ectasia Using Pulse or Continuous UV-A Light Phase 3
Completed NCT03913338 - Laser In-situ Keratomileusis With Crosslinking Compared to Conventional LASIK in Patients With High Myopia N/A
Terminated NCT01459679 - Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery Phase 3
Withdrawn NCT01643252 - Safety and Efficacy Study for Corneal Collagen Cross-Linking in Eyes With Corneal Ectasia After Refractive Surgery Phase 3
Active, not recruiting NCT04698590 - Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism N/A
Completed NCT04177082 - Safety and Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution Phase 1
Recruiting NCT06347900 - Corneal Topographic Changes in Different Grades of OSA