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NCT04267991 Clinical Trial

Corneal Densitometry Changes With Adenoviral SEI

Corneal Disease Clinical Trial

Official title:
Corneal Densitometry Changes With Adenoviral Keratoconjunctivitis Sub Epithelial Infiltrates

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04267991
Other study ID # Hamaky5
Secondary ID
Status Completed
Phase
First received
Last updated
Start date April 1, 2018
Est. completion date April 15, 2020

Study information
Verified date May 2020
Source Benha University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Adenoviral Sub epithelial infiltrates (SEI) affect ocular function.They lead to reduced vision, photophobia, glare, halos, and foreign body sensation.

Description:

first group of patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.S econd group underwent transepithelial PTK for subepithelial infiltrates. Baseline and post-treatment full ophthalmic examination was done.

Recruitment information / eligibility
Status Completed
Enrollment 63
Est. completion date April 15, 2020
Est. primary completion date April 1, 2020
Accepts healthy volunteers
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria:

- adenoviral SEI

Exclusion Criteria:

- Other corneal diseases

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Tacrolimus ointment
Patients were treated with 0.03 % tacrolimus ointment twice daily for 6 months.
Procedure:
• phototherapeutic keratectomy
Patients underwent transepithelial PTK for subepithelial infiltrates.

Locations
Country Name City State
United Arab Emirates INMC Abu Dhabi

Sponsors (1)
Lead Sponsor Collaborator
Benha University

Country where clinical trial is conducted

United Arab Emirates, 

Outcome
Type Measure Description Time frame Safety issue
Primary changes of corneal densitometry Sub epithelial infiltrates was examined with the densitometry programme of the Pentacam (Fa. Oculus,Weimar, Germany) 6 months
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