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Effect of HIgh-flow Therapy in Long-term Oxygen Therapy — HILOT  

Interstitial Lung Disease Clinical Trial

Official title:
Effect of HIgh-flow Therapy in Long-term Oxygen Therapy (HILOT): A Multicenter, Registry-based, Randomized Clinical Trial

Clinical Trial Summary

This is a registry-based, randomized, controlled clinical trial of the effect of added high-flow oxygen therapy (using the device Lumis HFT) during one year in people with long-term oxygen therapy (LTOT) for chronic obstructive pulmonary disease (COPD) or interstitial lung disease (ILD).

Clinical Trial Description

This is a registry-based, randomized, controlled clinical trial of patients with LTOT for COPD or ILD recruited using the Swedish National Registry for Respiratory Failure (Swedevox) in collaboration with a research network within the Swedish Respiratory Society. The trial evaluates the effect of added high-flow oxygen therapy nighttime to the regular low-flow oxygen therapy compared with regular low-flow oxygen therapy alone up to one year. The purpose of this project is to improve evidence-based treatment of people with chronic respiratory failure, currently about 2000 patients annually in Sweden, who have high risk of adverse events and mortality. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06247397
Study type Interventional
Source Skane University Hospital
Contact Magnus Ekström, MD, PhD
Phone 0455731000
Email magnus.ekstrom@med.lu.se
Status Recruiting
Phase N/A
Start date June 10, 2024
Completion date December 2028
View Details
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