Chronic Obstructive Pulmonary Disease Severe Clinical Trial
Official title:
Effects of a Comprehensive Health Coaching Program on Lung Function, Exercise Tolerance, Symptom Distress, Quality of Life, Readmission, and Survival in Advanced Chronic Obstructive Pulmonary Disease Patients: A Randomized Controlled Trial.
Chronic obstructive pulmonary disease due to incurable and prevalence has increased steadily,
chronic respiratory disease is considered hazardous to health and quality of life of the
disease. GOLD treatment guidelines (global initiative for chronic obstructive lung disease
guideline) pointed out the pulmonary rehabilitation is one of the non-drug treatment in
patients with severe COPD, shown to improve exercise capacity and reduce the short of
breathing, improve the quality of life and reduce the anxiety associated and depression and
improved survival advantages. Meanwhile, a few studies have examined effect the exercise
training in severe COPD patients' symptom distress and quality of life, so as to make severe
COPD patients to improve the effectiveness of the campaign to ongoing regular pulmonary
rehabilitation movement, is considered an important issue.
It has been proposed that physical activity enhancement or exercise training can be effective
in improving symptoms and quality of life in these patients. However, it has not been
examined systematically. Therefore, the main purposes of this study are: 1.Prevalence of
symptom distress; 2.The physical preferences; 3.The relationship between quality of life and
physical activity; 4.Effects of Comprehensive Health coaching exercise training on improving
fatigue, sleep disturbances, quality of life, readmission, and survival. In the first year of
this study, a descriptive-correlational design will be used and in the second and third years
of study, the experimental design and prospective longitudinal study will be undertaken.
Instruments include motion sensors, physical activity scale, Physical Activity Preferences,
Pittsburgh Sleep Quality of Life Index. Statistical analyses include descriptive statistics,
t-test, one-way ANOVA, latent growth modeling, Logistic models, GEE, and survival analysis.
Results from this study will provide important implications for improving symptom management
and quality of life for sever chronic obstructive pulmonary disease patients.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT03923660 -
Ventilatory Adaptation to Concentric Versus Eccentric Exercise in Patients With Severe COPD
|
N/A | |
| Not yet recruiting |
NCT06008210 -
A Decision Aid on End-of-life Care for Patients With Advanced COPD and Their Family
|
N/A | |
| Recruiting |
NCT05029349 -
Exploration of the VOLATOLOM in the Stable Severe COPD (Chronic Obstructive Pulmonary Disease)
|
N/A | |
| Not yet recruiting |
NCT05539547 -
Effect of NMES on Quadriceps Muscle Strength and Endurance in Patients With COPD
|
Early Phase 1 | |
| Recruiting |
NCT04018729 -
Cell Therapy Associated With Endobronchial Valve
|
Phase 2/Phase 3 | |
| Suspended |
NCT04848012 -
Efficacy of an Advanced Auto-titrating NIV in COPD
|
N/A | |
| Recruiting |
NCT06198309 -
Risk Prediction Model for Exacerbating Phenotype in Patients With Chronic Obstructive Pulmonary Disease
|
||
| Completed |
NCT05259280 -
Observational Study of the Wellinks Solution Impact on Quality of Life and Clinical Outcomes in Patients With COPD
|
N/A | |
| Not yet recruiting |
NCT06212765 -
Oral Citrulline Supplementation in COPD Patients With Malnutrition
|
Phase 3 | |
| Completed |
NCT02962999 -
Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation
|
Phase 4 | |
| Not yet recruiting |
NCT06229509 -
Study of the Cytokine Response During Exercise Dyspnea in Patients With Chronic Obstructive Pulmonary Disease (COPD). Effect of Body Composition
|
N/A | |
| Completed |
NCT05431218 -
Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD
|
Phase 4 | |
| Recruiting |
NCT04069312 -
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
|
Phase 3 | |
| Recruiting |
NCT05575336 -
Assessment of the Effectiveness, Socio-economic Impact and Implementation of a Digital Solution for Severe Patients
|
N/A | |
| Completed |
NCT02998515 -
Effects of Different Oxygen Devices in Hypoxemic COPD Patients
|
N/A | |
| Completed |
NCT04533516 -
Additional Manual Therapy Over Inspiratory Muscle Training in COPD
|
N/A | |
| Not yet recruiting |
NCT06247397 -
Effect of HIgh-flow Therapy in Long-term Oxygen Therapy
|
N/A | |
| Recruiting |
NCT06072690 -
Respiratory and Cardiovascular Alterations in Patients With Chronic Obstructive Pulmonary Disease
|