COPD Clinical Trial
Official title:
COPD, Inflammation and Rehabilitation
Patients with chronic obstructive pulmonary disease, also known as COPD or emphysema, is
like any other with a chronic illness not only affected by the physical discomfort the
illness gives. For COPD patients that is: accelerated loss of lung function, conditioning
and increased mortality: 25% of patients hospitalized with COPD exacerbation die 12 months
later.
Patients are also characterized by various psychological factors such as reduced quality of
life, depression, etc.
Therefore, everywhere in the country newly diagnosed COPD patients are offered
rehabilitation in Region Zealand which consists of 10 weeks of classes 2 hours, 2 times a
week with physical exercise, smoking cessation, medication, nutrition education and
psychosocial support and patient education based on the National Health Service and
international recommendations.
In the literature, the effect of rehabilitation on quality of life was measured using a
questionnaire (St. George Respiratory Questionnaire (SGRQ)), and the increase in function
has been measured using a walk test, but there are no studies which look at the effect on
inflammation lungs.
It is important for COPD patients is to prevent exacerbations of the disease, which
sometimes requires hospitalization and sometimes treated by their own doctor. It has been
proven that inflammation in the lungs is associated with disease severity and exacerbation
frequency, and therefore we would like to investigate whether both rehabilitation, close
monitoring of patients with time in the pulmonary clinic every 3 months, and instruction in
self-administration of medication (antibiotics and corticosteroids) have an effect on
especially inflammation in the lungs, number of exacerbations, mortality, lung function and
walking capacity.
n/a
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