Clinical Trials Logo
  1. Home
  2. Copd Exacerbation Acute
  3. NCT04000451

A Therapy for Improving Symptoms in Patients With Acute Exacerbations of COPD by Hydrogen-Oxygen Generator With Neburlizer.

Copd Exacerbation Acute Clinical Trial

Official title:
A Therapy for Improving Symptoms in Patients With Acute Exacerbations of Copd by an Hydrogen-Oxygen Generator With Neburlizer: A Multi-centric, Randomized, Parallel-control and Double-blinded Clinic Study

Clinical Trial Summary

The purpose for this study is to determine safety and effectiveness of the oxyhydrogen generator with nebulizer through a therapy for improving symptoms in patients with acute exacerbations of copd.

Clinical Trial Description

In this study, patients with acute exacerbations of copd who were included in both treatment and control groups, administered randomly oxyhydrogen generator with nebulizer (treatment group) or oxygen Nebulizer Machine (control group for the therapy. The therapeutic outcomes in both treatment and control groups are analyzed and evaluated to verify safety and effectiveness of the test product. This study is a multi-center, randomized, double-blind study. The trial lasted for about 10 days. The curative effect was observed for subjects in the First, the second, the third, the fourth, the fifth, the sixth, the seventh day, respectively as the observing time point. Total patients which are planned to be included are 108 cases, where, 54 cases in the treatment group and control group respectively are distributed in 10 clinical hospitals ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04000451
Study type Interventional
Source Shanghai Asclepius Meditec Inc.
Contact
Status Completed
Phase N/A
Start date January 7, 2019
Completion date September 20, 2019
View Details
See also
  Status Clinical Trial Phase
Terminated NCT05418777 - Treatment of Pneumocystis in COPD (the TOPIC Study) Phase 1/Phase 2
Not yet recruiting NCT05649891 - Checklists Resuscitation Emergency Department N/A
Completed NCT03286855 - Effectiveness of Vibrating Mesh Versus Small Volume Nebuliser in Chronic Obstructive Pulmonary Disease (COPD) N/A
Recruiting NCT06021990 - Clopidogrel for the Prevention of Exacerbations in Severe COPD Phase 3
Completed NCT05218525 - Testing a Prediction Algorithm Into a Running Telehealth System for Patients With COPD N/A
Recruiting NCT06149494 - RCT of Vapendavir in Patients With COPD and Human Rhinovirus/Enterovirus Upper Respiratory Infection Phase 2
Recruiting NCT05734365 - COPD-ICU Multicentre Prospective Observational Register
Completed NCT03464695 - Automated Oxygen Delivery by O2matic to Patients Admitted With an Exacerbation in COPD N/A
Recruiting NCT04881409 - Nasal High-flow Compared to Non-invasive Ventilation in Treatment of Acute Acidotic Hypercapnic Exacerbation of Chronic Obstructive Pulmonary Disease N/A
Completed NCT05182294 - Tolerance and Acute Effects of a New HFNT Nasal Cannula N/A
Completed NCT04821869 - ProAir Digihaler in COPD Disease Management: A Real World Study
Not yet recruiting NCT06274957 - The Effect of Airway and Chest Wall Oscillation on Respiratory Functions in COPD Patients in Acute Exacerbation N/A
Recruiting NCT05783544 - Impact of A. Lumbricoides on Pulmonary Aspergillosis Development N/A
Recruiting NCT06331416 - Multiparametric Home Telemonitoring of Patients With Chronic Obstructive Pulmonary Disease Exacerbation N/A
Not yet recruiting NCT05703919 - Standard vs Targeted Oxygen Therapy Prehospital for Chronic Obstructive Pulmonary Disease Phase 4
Recruiting NCT05764993 - Prevalence of Humoral Dysfunction in Pts With Frequent Exacerbations of COPD, and the Effect of SCIgR for Prevention Phase 2
Completed NCT06040931 - Airway Inflammation, Small Airways Dysfunction, and Frequency of Exacerbations in COPD N/A
Active, not recruiting NCT04192175 - Identification of Patients Admitted With COPD Exacerbations and Predicting Readmission Risk Using Machine Learning
Recruiting NCT03680495 - Steroid Resistance During COPD Exacerbations With Respiratory Failure
Recruiting NCT05452226 - Neuromuscular Electrical Stimulation in COPD/Community Acquired Pneumonia N/A