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Contact Lens clinical trials

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NCT ID: NCT06335212 Completed - Myopia Clinical Trials

Peripheral Defocus Profile of Multifocal Minus Contact Lenses

Start date: June 1, 2019
Phase:
Study type: Observational

Purpose: Numerous studies have proven that emmetropization in young animals including humans is regulated by visual input. It has long been hypothesized that peripheral myopic defocus may act as a stop signal to reduce myopia progression and axial elongation. As such, multifocal soft contact lenses (MFCLs) have been utilized for myopia control in school-aged children, with variable efficacies. One potential explanation is that the actual peripheral myopic defocus an eye experiences during MFCL wear may not be identical to the Add power and not sufficient to reduce myopia progression. Our study investigated and compared the peripheral power profiles of myopic eyes when they were uncorrected and wore single vision contact lenses (SVCLs) and MFCLs of different Add powers. Methods: Subjects with -1.00 D to -10.00 D of myopia (SE, determined with manifest refraction) were custom fit with both single vision (SV) and MFCLs (+2.00 and +4.00 D Add; provided by Specialeyes) in both eyes. These Specialeyes MFCLs had an aspheric design with a standard total optical zone of 8.0mm. Cycloplegic central autorefraction was conducted with both Grand Seiko WAM-5500 open-field auto-refractor (Grand Seiko Co Ltd) and OPD OPD-Scan III Wavefront Aberrometer (Marco) on the subjects in the following conditions: (1) no CLs, (2) SVCLs, (3) MFCLs (+2.00D Add), and (4) MFCLs (+4.00D Add). Relative peripheral power profiles were measured using the OPD under the same 4 conditions after cycloplegia. Data in the right eye was used for analysis.

NCT ID: NCT05416528 Completed - Questionnaire Clinical Trials

Chinese Translation and Validation of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8)

CLDEQ-8
Start date: November 18, 2022
Phase:
Study type: Observational

This is a cross-cultural adaptation, evaluation and validation study of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among soft contact lens wearers in China.

NCT ID: NCT05102383 Completed - Contact Lens Clinical Trials

Evaluation of Wear Experience With a Water Surface Daily Disposable Contact Lens

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the wear experience of existing wearers of a monthly replacement contact lens after they have been fit with a daily disposable contact lens that has water surface treatment.

NCT ID: NCT05096156 Completed - Contact Lens Clinical Trials

Evaluation of Wear Experience With Daily Contact Lenses

Start date: May 28, 2021
Phase: N/A
Study type: Interventional

To evaluate the wear experience of current monthly replacement contact lens wearers after they have been fit into a daily disposable contact lens.

NCT ID: NCT04844281 Completed - Contact Lens Clinical Trials

Wear Experience With Daily Toric Contact Lenses Over a Long Day

Start date: May 11, 2021
Phase: N/A
Study type: Interventional

This study is evaluating the wear experience of a daily toric contact lens after 10, 12, 14, and 16 hours of lens wear.

NCT ID: NCT04535310 Completed - Contact Lens Clinical Trials

Wear Experience With Daily Contact Lenses Over a Long Day

Start date: October 13, 2020
Phase: N/A
Study type: Interventional

This study is evaluating the wear experience of a daily contact lens after 10, 12, 14, and 16 hours of lens wear.

NCT ID: NCT04296877 Completed - Contact Lens Clinical Trials

Evaluation of Wear Experience With a Daily Disposable Contact Lens

Start date: March 10, 2020
Phase: N/A
Study type: Interventional

To evaluate the wear experience of current two-week contact lens wearers after they have been fit into a daily disposable contact lens. This is a single arm, non-comparative study.

NCT ID: NCT03686878 Completed - Clinical trials for Contact Lens Discomfort

Lifitegrast 5% Ophthalmic Solution and Contact Lens Dryness

Start date: December 16, 2016
Phase: Phase 4
Study type: Interventional

The most common reason for contact lens discontinuation is contact lens discomfort. The investigators believe that inflammation plays a role in contact lens discomfort and the use of lifitegrast 5% ophthalmic solution may reduce end of the day contact lens discomfort. This study will enroll 21 contact lens users who will be receiving lifitegrast 5% ophthalmic solution and monitor the contact lens discomfort for a 8 week period while.

NCT ID: NCT02713399 Recruiting - Contact Lens Clinical Trials

High-resolution Imaging of Tear Film Thickness in Contact Lenses Wearers With Optical Coherence Tomography (OCT). A Pilot Study

Start date: March 16, 2016
Phase:
Study type: Observational

A refractive error is the most common reason for reduced visual acuity. Myopia, hyperopia, astigmatism and presbyopia belong to the four basic refractive errors and, unfortunately, cannot be prevented. There are different tools to correct them, like spectacles, contact lenses, and refractive surgery. Many different contact lenses are available, the two large groups create rigid contact lenses and soft contact lenses. It is a common knowledge that the presence of a contact lens in the eye divides the tear film into the prelens and postlens tear film layers. In the present study we want to investigate the variability and reproducibility of prelens and postlens tear film thickness measurements.