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Constriction, Pathologic clinical trials

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NCT ID: NCT04307888 Not yet recruiting - Clinical trials for Aortic Valve Stenosis

Spanish Percutaneous Aortic INtervention REGISTRY (SPAIN REGISTRY)

SPAIN
Start date: April 2020
Phase:
Study type: Observational [Patient Registry]

Multicentre prospective registry including consecutive patients undergoing Percutaneous Endovascular Aneurysm Repair (PEVAR), Percutaneous Endovascular Thoracic Aneurysm Repair (PTEVAR) or Transcatheter Aortic Valve Implantation (TAVI) in which variables related to the percutaneous access closure for implanting devices at aorta level will be collected and analyzed. The follow-up period will be 30 days after the procedure. The duration of the recruitment period will be one year. All data will be collected telematically and incorporated into a database for subsequent statistical analysis. There will be 2 points for data interim analysis at 6 and 12 months after initiation of the study.

NCT ID: NCT04303351 Not yet recruiting - Clinical trials for Atherosclerosis of Artery

Periodontitis and Atherosclerotic-related Arterial Stenosis

Start date: April 2020
Phase:
Study type: Observational

This study aimed to evaluate the association between periodontitis and atherosclerosis of the cerebral vasculature in the Chinese population.

NCT ID: NCT04221867 Not yet recruiting - Clinical trials for Esophageal Stricture

Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Esophageal Strictures (ESOGRAFT)

ESOGRAFT
Start date: August 15, 2021
Phase: N/A
Study type: Interventional

In this study the investigators investigate the feasibility and therapeutic potential of free autologous fat grafting combined to dilation therapy in the treatment of benign esophageal strictures.

NCT ID: NCT04175197 Not yet recruiting - Clinical trials for Peripheral Arterial Disease

LegDeb2 Global Registry for Use of Legflow in Peripheral Arteries

LEGDEB2
Start date: November 2019
Phase:
Study type: Observational

LEGDEB2 is a Global Registry for the Treatment of Superficial Femoral and/or Popliteal or Below-The-Knee or Iliac Artery Lesions Using the Legflow Drug-Eluting Balloon

NCT ID: NCT04124627 Not yet recruiting - Clinical trials for Lumbar Stenosis, Familial

Place of Ultrasound Guidance of Surgery Site in Surgery for Lumbar Canal Stenosis and Lumbar Disc Herniations

Start date: December 1, 2019
Phase: N/A
Study type: Interventional

The identification of the operative site of lumbar ductal stenosis and lumbar disc herniation is classically done by radioscopy, thus inducing irradiation of the patient. The use of ultrasound in spine surgery is little studied and poorly mentioned in the scientific literature. However, it is commonly used for other types of scouting (especially anesthetics). Thus, in the absence of consensus and clear recommendations, some practitioners perform ultrasound scans . Methodological developments also validate the feasibility of the ultrasound approach. The double benefit of an ultrasound identification is firstly a lack of exposure to X-rays for both the patient and the operating team and secondly a lower cost than a conventional radiography. The main objective is to demonstrate the interest of the ultrasound identification of the surgical site in the intervention of lumbar ductal stenosis and lumbar disc herniations in terms of concordance of the operating site between ultrasound and fluoroscopy.

NCT ID: NCT04124146 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Long-term Evolution of Patients Suffering From Lumbar Canal Stenosis and Supported by Minimally Invasive Surgery: SUIVISTENO

SUIVISTENO
Start date: December 1, 2019
Phase:
Study type: Observational

describe the functional evolution of patients at more than 10 years post intervention. describe the evolution of pain, satisfaction, quality of life of patients to more than 5 years pot intervention.

NCT ID: NCT04075539 Not yet recruiting - Clinical trials for Symptomatic Lumbar Spinal Stenosis

Home-based Cycling for People With Lumbar Spinal Stenosis

FLEXCAL
Start date: March 2023
Phase: Phase 3
Study type: Interventional

The main objective of the study is to compare the efficacy on back-specific activity limitations at 4 months after-randomisation of home-based cycling using connected ergometric bicycles associated with usual care to usual care.

NCT ID: NCT03999008 Not yet recruiting - Esophageal Atresia Clinical Trials

Oral Viscous Budesonide in Anastomotic Stricture After Esophageal Atresia Repair (OVB in EA)

OVB in EA
Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to perform a multicentre, prospective, randomized, placebo controlled, double-blinded study to demonstrate the potential and beneficial effects of OVB in the prevention of recurrence of anastomotic stricture in children operated for esophageal atresia with an anastomotic stricture.

NCT ID: NCT03918512 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Development and Validation of a Questionnaire for Assessing Activity Limitation in Patients With Lumbar Spinal Stenosis : The Cochin L3S Questionnaire

CL3S
Start date: March 1, 2020
Phase:
Study type: Observational

To develop and validate a questionnaire aiming at assessing specific activity limitation in patients with lumbar spinal stenosis (LSS).

NCT ID: NCT03892837 Not yet recruiting - Clinical trials for Benign Airway Stenosis

Clinical Study on Autologous Platelet-rich Plasma (PRP) Treatment for Refractory Benign Airway Stenosis

Start date: April 2019
Phase: N/A
Study type: Interventional

Platelet-rich plasma(PRP), is a concentrate of platelet-rich plasma protein derived from whole blood. The main components of it are platelets, leukocytes and fibrin. Autologous PRP treatment can avoid the immune rejection caused by exogenous growth factor and the spread of disease. Evidence of the efficacy and safety of PRP has been proven in many studies. Benign central airway stenosis is characterized by airway compromise involving the larynx, trachea, or bronchi and will lead to devastating consequences. Unfortunately, the incidence of this disease is increasing steadily. As most important treatment for benign airway stenosis, respiratory intervention has become one of the most common treatments to fight the disease. However, the restenosis caused by tissue hyperplasia, wound repair and scar formation after treatment is still common, which remains the limitation of respiratory intervention. Long-term efficacy of repeated interventional treatment is unsatisfying, too. Several studies have discovered similar mechanism between stenosis of tracheal to hyperplastic scar of skin, both of which are relative with deep structure injury such as the intrinsic layer of airway mucosa. PRP has shown significant efficacy for hyperplastic scar of skin. Correspondingly, PRP will be applied as treatment of refractory benign airway stenosis to reduce restenosis by inhibit the formation of granulation.