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Constriction, Pathologic clinical trials

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NCT ID: NCT04778943 Not yet recruiting - Clinical trials for Lumbar Spinal Stenosis

Oblique Lateral Interbody Fusion Versus Minimally Invasive Transforaminal Lumbar Interbody Fusion

Start date: February 28, 2021
Phase:
Study type: Observational

The investigators will retrospectively study lumbar spinal stenosis patients who underwent OLIF or MIS-TLIF with percutaneous pedicle screw fixation between January 2016 and December 2019.The investigators will measure estimated blood loss, operative time, hospital stay, cost, reoperation, and complication incidence, visual analogue scale (VAS), Oswestry Disability Index (ODI), Japanese Orthopaedic Association (JOA), and Short Form-36 (SF-36) scores, discal and foraminal height, lumbar lordotic angle, and fusion status.The investigators will conduct to evaluate postoperative improvements, complications, and reoperation rates between patients with lumbar spinal stenosis (LSS) undergoing oblique lateral interbody fusion (OLIF) or minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF).

NCT ID: NCT04625400 Not yet recruiting - Tracheal Stenosis Clinical Trials

Role of Bronchoscopy in Assessment of Patients With Post-intubation Tracheal Stenosis

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

1. To estimate the importance of bronchoscopic treatment of tracheal stenosis and its effectiveness and safety. 2. To diagnose and evaluate tracheal stenosis characteristics as location, vertical extension and severity of obstruction.

NCT ID: NCT04569669 Not yet recruiting - Coronary Stenosis Clinical Trials

The Sensitivity and Specificity of CardioSimFFRct Analysis Software on Coronary Artery Stenosis

Start date: October 9, 2020
Phase: N/A
Study type: Interventional

The device involved in this trail is a diagnostic software with a Prospective, Multicenter, Self Controlled design. FFRCT diagnostic performance was calculated by CardioSimFFRct Analysis software, and the diagnostic accuracy, sensitivity, specificity, positive predictive value and negative predictive performance of FFRCT for myocardial ischemia were calculated per-patient level and per-vessel level with invasive FFR value as gold standard.

NCT ID: NCT04550819 Not yet recruiting - Bile Duct Stricture Clinical Trials

Intraintestinal Extended Biliary Stents Preventing Duodenobiliary Reflux in Patients With Biliary Stricture

Start date: October 2020
Phase: N/A
Study type: Interventional

Metal or plastic biliary stents placement under Endoscopic Retrograde Cholangiopancreatography(ERCP) is a well-established treatment for patients with benign biliary obstruction to relieve jaundice, a palliative treatment for patients with unresectable malignant pancreaticobiliary obstruction and a bridge to surgery for patients with resectable disease. The main limitation of long time plastic stents is stents occlusion. Biliary plastic stents are changed every 2 to 3 months due to an expected median patency from 77 to 126 days.Metal stents present a lower risk of recurring biliary occlusion, yet high cost and stents occlusion are eventually inevitable. The mechanism of biliary stents occlusion include biliary sludge of the accumulation of bacteria and duodenal biliary reflux .The anti-reflux barrier of Oddi's sphincter disappears after the insertion of biliary stents and the pressure in bile duct lowers the duodenale, which cause the retrograde flow of duodenal material into the biliary ducts. Besides, ordinary biliary plastic stent is short which can also shortens the length of duodenal biliary reflux . Therefore, trying to prevent the duodenal biliary reflux is very important in reducing biliary stents occlusion and it is gradually concerned by clinical researchers. Some studies have showed that plastic stents with antireflux valves can effectively reduce the biliary stent stricture and prolong the stents patency, which means reducing duodenobiliary reflux is surely useful for keeping biliary stent patency.So,we assume to explore an innovatively intraintestinal extended biliary stents (reformed with nasobiliary tube ) as substitution for ordinary biliary plastic stent to prevent the duodenobiliary reflux by extending the length of duodenal content reflux and avoid the stents shift via suspending in intrahepatic duct. In this study,we will design a multicenter stratified randomized controlled trial to compare the patency of intraintestinal extended biliary stents and ordinary plastic biliary stents in patients with malignant or benign biliary obstruction respectively and evaluate the effect of intraintestinal extended biliary stents for the prevention of duodenobiliary reflux.

NCT ID: NCT04545281 Not yet recruiting - Clinical trials for Peripheral Arterial Disease

Physician-Initiated PMCF Trial Investigating the Solaris Vascular Stent Graft for the Treatment of Iliac Lesions

SOLARIS-PMCF
Start date: January 2, 2021
Phase: Phase 4
Study type: Interventional

The objective of this clinical investigation is to evaluate, in a controlled setting, the long-term (up to 12 months) safety and efficacy of the Solaris Vascular Stent Graft (Scitech) in clinical settings when used according to the indications of the IFU.

NCT ID: NCT04524897 Not yet recruiting - Clinical trials for Esophageal Stricture

The Use of Triamcinolone Injection in Treatment of Refractory Benign Esophageal Stricture in Children

Start date: December 1, 2020
Phase: Phase 4
Study type: Interventional

To evaluate the efficacy of Intra-lesional triamcinolone injection in the management of refractory benign esophageal Stricture in children.

NCT ID: NCT04503330 Not yet recruiting - Clinical trials for Pelvi Ureteric Junction Obstruction or Ureteral Stricture

Buccal Mucosal Graft for the Repair of Iatrogenic Pelviureteric Junction Obstruction or Ureteric Stricture.

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Prospective study to evaluate the safety and efficacy of using buccal mucosal graft for repairing complex cases of iatrogenic pelvi ureteric junction obstruction and long segment ureteric stricture disease.

NCT ID: NCT04399564 Not yet recruiting - Clinical trials for Stenosis of Arteriovenous Dialysis Fistula

Temporary vs.Long Term Hemodialysis Catheter on Central Vein Stenosis

Start date: May 25, 2021
Phase: N/A
Study type: Interventional

Vascular access (VA) is the most important for carrying out hemodialysis, yet it may bring in complications and leads to hemodialysis quality decline. This study aimed to explore the impact of vascular access types, including temporary vs.long term hemodialysis catheter on central vein stenosis.

NCT ID: NCT04372784 Not yet recruiting - Clinical trials for Esophageal Stricture

Cryoablation for Benign Gastrointestinal Anastomotic Strictures

Start date: September 2020
Phase: N/A
Study type: Interventional

Anastomotic stricture is a common complication following foregut surgery. The standard of care for these benign foregut anastomotic strictures is balloon dilatation. However, re-stenosis of strictures is also common, requiring frequent repetition of balloon dilatation. Cryotherapy is a novel therapy that may improve clinical outcomes following dilatation. The purpose of the present study is to conduct a randomized controlled trial to characterize the impact of cryotherapy on clinical outcomes and complications for benign anastomotic strictures following esophagectomy, gastrectomy, and bariatric surgery.

NCT ID: NCT04318795 Not yet recruiting - Spinal Stenosis Clinical Trials

MIS-D Versus MIS-TLIF for the Treatment of Lumbar Spinal Stenosis

Start date: June 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the effectiveness of two minimal invasive spine surgery, minimally invasive spinal decompression (MIS-D) and minimally invasive spinal decompression and fusion (MIS-TLIF), for patients diagnosed with lumbar spinal stenosis in terms of clinical outcomes, complications, reoperations, and other perioperative data.