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Constriction, Pathologic clinical trials

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NCT ID: NCT01522573 Recruiting - Pancreatic Cancer Clinical Trials

T-EUS for Gastrointestinal Disorders: A Multicenter Registry

EUSERCPReg
Start date: November 2011
Phase: N/A
Study type: Observational

The purpose of this registry is to record information and evaluate the impact of Endoscopic Ultrasound (EUS) Guided Endoscopic retrograde cholangiopancreatography (ERCP) on the management of pancreatico-biliary disorders. The registry will evaluate efficacy, safety and technical success of the Endoscopic Ultrasound (EUS)Guided Endoscopic retrograde cholangiopancreatography (ERCP) procedures. The safety and efficacy of various EUS-Guided ERCP procedures have been assessed in a series of studies. This multi-center registry has been initiated: - To document the impact of EUS-Guided ERCP procedures on the management of pancreatico-biliary disorders including malignancies. - To assess the clinical and technical success rates of EUS-Guided ERCPs for diagnostic or therapeutic procedures. Design is retrospective and prospective registry study. Procedures that will be captured include: 1. EUS-Coils placement 2. EUS Glue injection 3. EUS-Fiducial placement 4. EUS-Neurolysis 5. EUS-Stent placement 6. EUS-alcohol injection 7. EUS-fluid collection, abscess or cavity drainage 8. EUS guided ductal drainage 9. EUS-guided Ablation 10. EUS-guided anastomosis 11. EUS Guided ERCP for gallbladder, pancreatic duct or biliary duct drainage

NCT ID: NCT01456377 Recruiting - Clinical trials for Spinal Stenosis of Lumbar Region

The Effectiveness of Oral Corticosteroids in the Treatment of Lumbar Stenosis

Start date: July 2011
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effectiveness of the use of systemic corticosteroids administered orally in narrow lumbar canal syndrome.

NCT ID: NCT01439698 Recruiting - Pancreatic Cancer Clinical Trials

Radio Frequency Ablation in the Management of Pancreatico-biliary Disorders: A Multicenter Registry

RFA-Registry
Start date: September 2011
Phase: N/A
Study type: Observational [Patient Registry]

The objective of this protocol is to establish a multicenter registry to evaluate the impact of radiofrequency ablation in the management of patients with pancreatico-biliary disorders including malignancies.

NCT ID: NCT01414361 Recruiting - Clinical trials for Coronary Artery Stenosis

Fractional Flow Reserve and Intravascular Ultrasound in Evaluating Intermediate Coronary Lesions

Start date: March 2009
Phase: Phase 4
Study type: Observational

Recent studies have shown that optimal IVUS criteria defining the functional significance (FFR < 0.8) of intermediate coronary stenoses is different according to their locations of the coronary tree. Herein, the investigators performed this study to validate these results and to generalize the IVUS criteria defining functional significance of intermediate coronary stenosis in a different location of coronary tree in a larger sample size.

NCT ID: NCT01196572 Recruiting - Urethral Strictures Clinical Trials

Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures

IU
Start date: September 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether laser internal urethrotomy (IU) is as efficient as cold knife internal urethrotomy for treatment of anterior urethral strictures regarding post operative urination outflow, stricture recurrence rate and possible post- operative complications

NCT ID: NCT01173666 Recruiting - Clinical trials for Left Ventricular Hypertrophy

Stenting of Renal Artery Stenosis in Coronary Artery Disease Study

RASCAD
Start date: April 2006
Phase: Phase 3
Study type: Interventional

The Stenting of Renal Artery Stenosis in Coronary Artery Disease (RASCAD) study is a randomized controlled trial designed to evaluate the effect of renal artery stenting+medical therapy versus medical therapy alone on left ventricular mass progression and cardiovascular morbidity and mortality in patients affected by coronary artery disease and renal artery stenosis.

NCT ID: NCT01118442 Recruiting - Clinical trials for Aortic Valve Stenosis

Determination of the Acute Effects of Aortic Stenosis on Coronary Artery Haemodynamics

Start date: December 2009
Phase: N/A
Study type: Observational

Narrowing of the main valve which controls blood leaving the heart leads to a marked increase in death. To overcome this narrowing the heart muscle thickens abnormally and contracts more vigorously. However, in doing so, blood flow patterns to the heart muscle change through mechanisms which are incompletely understood. New technology allows such heart valve blockages to be fixed using balloons and metal stents inserted through tubes placed in arteries in the leg. Using sensors placed in these tubes it is possible to make detailed measurements of coronary flow and pressure, and apply new mathematical techniques to allow a better understanding of the detrimental effects that aortic stenosis has on coronary flow, before and after valve surgery.

NCT ID: NCT00811330 Recruiting - Clinical trials for Aortic Valve Stenosis

Effects of High Dose Atorvastatin in Patients With Surgical Aortic Stenosis

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of the study is to see if statin therapy will optimize myocardial response to cardiopulmonary bypass during aortic valve replacement (AVR) for aortic valve stenosis (AVS) (Phase I) and optimize left ventricular reverse remodeling following AVR (Phase II). Preliminary evidence indicates that perioperative statin therapy reduce mortality and morbidity following cardiac surgery. Pleiotropic effects of statins may induce myocardial preconditioning and optimize myocardial and systemic responses to cardiopulmonary bypass during AVR. Furthermore statin therapy after AVR may contribute to an optimal left ventricular reverse remodeling.

NCT ID: NCT00767013 Recruiting - Coronary Disease Clinical Trials

Preoperative Assessment of Aortic Valve Stenosis and Coronary Artery Disease

Start date: May 2007
Phase: N/A
Study type: Interventional

We sought to determine whether the dual-source computed tomography assessment of aortic valve stenosis and coronary artery disease is equivalent to or even better than conventional invasive coronary angiography and transthoracic echocardiography.

NCT ID: NCT00737607 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Clinical Outcome Study of Minimally Invasive Decompression for Lumbar Spinal Stenosis

MEDLLSS
Start date: January 2008
Phase: N/A
Study type: Observational

The study is a prospective outcome study to evaluate the effectiveness and treatment outcomes of microendoscopic decompressive laminotomy (MEDL) with objective evaluation tools. The patients who fulfill the selection criteria will be enrolled to collect the pre-operative clinical data including demographic data, image studies, and functional evaluation for neurological symptoms and disability. The patient will receive MEDL and post-operative follow-up will be arranged at 1 week, 1 month, 6 months, and 12 months after the operation. All the collected data will be analyzed to evaluate the efficacy and treatment results of MEDL.