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Constriction, Pathologic clinical trials

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NCT ID: NCT04827238 Recruiting - Clinical trials for Aortic Valve Stenosis

Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)

Start date: August 30, 2021
Phase:
Study type: Observational

The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics) post-TAVR.

NCT ID: NCT04795570 Recruiting - Fibrosis Clinical Trials

Urethral Stricture After Transurethral Resection of the Prostate/Bladder: a Prospective Study of Risk Factors

STRICT-TURP
Start date: September 1, 2020
Phase:
Study type: Observational

There is currently no prognostic or predictive risk marker for this urethral stricture disease. The most conservative standard treatment for urethral stricture (internal urethrotomy) has a very high recurrence rate (greater than 75%) and, on many occasions, reconstructive urologists have to choose within a great variety of further complex interventions. Knowing risk and predictive markers of this disease could help to optimize both the need and the approach for these surgeries and may offer a more individualized management to patients.

NCT ID: NCT04795284 Recruiting - Clinical trials for Lumbar Spinal Stenosis

Biomechanical Parameters of Gait in Patients With Symptomatic Lumbar Spinal Stenosis and Healthy Elderly.

Start date: September 9, 2020
Phase:
Study type: Observational

The aim of this study is to compare biomechanical walking parameters between patients with symptomatic lumbar spinal stenosis and healthy elderly.

NCT ID: NCT04734483 Recruiting - Larynx Disease Clinical Trials

The Effectiveness of Reconstructive Microsurgery on the Clinical and Functional State of Laryngeal Stenosis

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

To improve diagnostic methods for patients with laryngeal stenosis for the optimal determination of the technique of surgical treatment.

NCT ID: NCT04722796 Recruiting - Aortic Stenosis Clinical Trials

HANGZHOU Solution in Bicuspid AS Undergoing TAVR

Start date: April 12, 2021
Phase: N/A
Study type: Interventional

To compare supra-annular sizing and THV implantation technique (Hangzhou solution) versus annular sizing and THV implantation technique (control group) in bicuspid aortic stenosis (AS) patients undergoing transcatheter aortic valve replacement (TAVR) with self-expanding valves (SEVs): a randomized superiority trial

NCT ID: NCT04719845 Recruiting - Tracheal Stenosis Clinical Trials

DilAtation Versus Endoscopic Laser Resection in Simple Benign trAcheal sTEnosis

AERATE
Start date: March 17, 2021
Phase: N/A
Study type: Interventional

Multicenter randomized controlled trial comparing endoscopic laser resection vs dilatation in benign tracheal stenosis.

NCT ID: NCT04717219 Recruiting - Clinical trials for Aortic Valve Stenosis

Myeloid Cells in Aortic Valve Stenosis

MIRACLE
Start date: November 19, 2020
Phase:
Study type: Observational

Investigators plan to characterize systemic inflammation and circulating immune cells in participants with moderate and severe calcific aortic valve disease and matched healthy controls.

NCT ID: NCT04714268 Recruiting - Aortic Aneurysm Clinical Trials

Comparison of Aorto-iliac Endovascular Interventions With and Without the EndoNaut Workstation

COM-ENDO
Start date: January 1, 2021
Phase:
Study type: Observational

The aim of this retrospective, multicenter study is to demonstrate that the use of EndoNaut for aortoiliac endovascular procedures has a clinical impact for the patient (reduction in irradiation and the volume of contrast product) as well as for the nursing staff (reduction irradiation) compared to procedures performed without EndoNaut.

NCT ID: NCT04703699 Recruiting - Clinical trials for Aortic Valve Stenosis

Myval Global Study of Myval™ THV Series Implanted in Patients With Native Severe Aortic Valve Stenosis.

Start date: August 7, 2020
Phase:
Study type: Observational

A retrospective, multinational, multicentre, observational study in patients presenting with native severe aortic valve stenosis and treated with Myval™ Transcatheter Heart Valve Series in real-world setting.

NCT ID: NCT04696289 Recruiting - Clinical trials for Pulmonary Vein Stenosis

Predicting Pediatric Pulmonary Vein Stenosis Outcomes Using Data Acquired During a Cardiac Catheterization

Start date: February 26, 2021
Phase: N/A
Study type: Interventional

This is a prospective, single center study which applies a standardized, comprehensive catheterization assessment to patients with a known or suspected diagnosis of pulmonary vein stenosis (PVS) who are undergoing a cardiac catheterization at Boston Children's Hospital. As part of the assessment, each pulmonary vein will undergo angiography (pictures using moving x-rays and contrast dye), intravascular ultrasound (IVUS; pictures of the vein wall using a catheter inside the vein), pressure assessment and compliance testing. The status of each pulmonary vein will then be assessed 12 months after the catheterization (i.e. no disease, severe disease, etc.). Using statistics, the investigators will determine which patient and vein characteristics (obtained at the of catheterization) can predict whether or not a pulmonary vein will have disease. The investigators hypothesize that this comprehensive, standardized, invasive assessment of pediatric intraluminal PVS can predict vein outcome.