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Constipation clinical trials

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NCT ID: NCT06175598 Completed - Surgery Clinical Trials

Analysis of the Causes of Redo Pull-through for Recurrent Constipation and the Risk Factors Affecting the Prognosis of the Hirschsprung's Disease and Allied Disorders

Start date: December 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to conducted a comprehensive analysis of the factors contributing to redo- Pull-through surgery for constipation recurrence in Children who are suffering from Hirschsprun' s disease (HSCR) and its allied disorders (ADHD) . The main question[s] it aims to answer are: 1. Our study focused on the treatment and prognosis of these conditions, drawing upon 16 years of patient data and clinical experiences" 2. What are the key risk factors affecting the prognosis of recurrent constipation patients undergoing repeat PT?

NCT ID: NCT06155929 Completed - Constipation Clinical Trials

Traveler's Constipation

Start date: May 2, 2023
Phase: N/A
Study type: Interventional

The occurence of traveler's constipation is sparsely covered in the medical litterature. This study aims to determine the gastrointestinal-related discomforts related to traveling on a trip to Turkey.

NCT ID: NCT06082622 Completed - Clinical trials for Constipation Chronic Idiopathic

Evaluation of the Triple Management Program in the Management of Functional Chronic Constipation in Children

Start date: March 2016
Phase: N/A
Study type: Interventional

Abstract Background: Chronic constipation is a common disease in children, 3% all children visit gastroenterology clinics with different types and complains. It is very harsh, time consuming and psychological problems to a child and all his family members. Objective: To find a simple and effective training method that manages the bowel habits intervals both easy and effective for both child and parents. Patients and methods: A training program for 18 weeks in 180 children with follow up every three months for 3 years between March 2016 and April 2019. Two groups were assembled, Group (A) with 90 children managed by the 3 Role program and Group (B) formed of the other 90 children treated with traditional guidelines. All types of functional Constipations and all ages are distributed equally in the two Groups. The Parents were taught to Hang a Sign Saying (One Bowel habit by third day at least) and then follow the Triple method program for 18 weeks. First follow up is on the 3rd week. The triple axis program is working on mental, colon elasticity and fecal consistency. The Mental axis is done by bowel interval sets in fixed 3 times for 10 minutes in each, Colon contents by certain diet protocol and colon motility and elasticity by drugs.

NCT ID: NCT05988502 Completed - Heart Failure Clinical Trials

Auricular Acupressure Relieves Constipation for Patients With Heart Failure in Hospital

Start date: March 6, 2022
Phase: N/A
Study type: Interventional

This study aimed to investigate the effect of auricular acupressure (AA) to relieve constipation symptoms and improve quality of life in patients hospitalized for their heart failure. A total of 72 participants were randomly assigned and 68 (33 in the AA group and 35 in the control group) completed the study. Outcomes were measured by the Bristolv Stool Form Scale, Constipation Assessment Scale, Patient Assessment of Constipation Symptoms, Visual Scale Analog, Beck Anxiety Inventory and Beck Depression Inventory at baseline, Weeks 1 and 2, as well as Constitution in Chinese Medicine Questionnaire and Patient Assessment of Constipation Quality of Life at baseline and Week 2.

NCT ID: NCT05983926 Completed - Constipation Clinical Trials

To Explore the Changes of Nutritional Status, Immune Function, Intestinal Motility and Intestinal Flora in Patients With Constipation Before and After Surgical Treatment

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Chronic constipation is a heterogeneous disease with multiple symptoms, and its incidence is on the rise in many countries. It has become a common disease affecting the quality of life. When these patients fail to respond to standardized and systematic non-surgical treatment, and the relevant examination suggests that there are surgical indications, surgical treatment should be considered. The cure rate of surgical treatment can reach 95%. The purpose of this study was to evaluate the intestinal motility, nutritional status, immune function and intestinal environment of patients by measuring BMI, biochemical tests and nutritional risk related questionnaires.

NCT ID: NCT05982743 Completed - Constipation Clinical Trials

Lactobacillus Casei Strain Shirota Fermented Milk for Alleviating Hard Stools in Vietnam

Start date: May 11, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to provide evidence supporting the efficacy of fermented milk containing Lactobacillus casei strain Shirota in alleviating hard or lumpy stools. A randomized, controlled trial has been designed on constipated adults with a high prevalence of hard stools in Vietnam.

NCT ID: NCT05980988 Completed - Clinical trials for Chronic Constipation

Effectiveness and Safety of Probiotic in Regulating Chronic Constipation

Start date: September 9, 2021
Phase: N/A
Study type: Interventional

To evaluate the effectiveness and safety of the use of probiotics as food supplements in regulating the intestinal habit of subjects with chronic constipation, in comparison with placebo.

NCT ID: NCT05770960 Completed - Clinical trials for Opioid-Induced Constipation

Colonic Motor Patterns in Healthy Volunteers

NaloxegolHRM
Start date: June 27, 2018
Phase: Phase 4
Study type: Interventional

Characterization of motor patterns with opioid agonists (codeine) ingestion, and their reversal by a peripherally acting mu-opioid receptor antagonist (Naloxegol).

NCT ID: NCT05742672 Completed - MASSAGE Clinical Trials

Investigation of the Effect of Abdominal Massage Applied to Palliative Care Patients on Constipation and Quality of Life

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

The problem of constipation plays a very important role among these symptoms that patients experience intensely and negatively affect their quality of life. Although constipation is not a disease, it is a condition that causes discomfort to the person and may develop due to idiopathic reasons, as well as depending on diet, exercise habits, medications used and various disease processes. It may also occur. Constipation is one of the most common symptoms in patients treated in palliative care, and its prevalence is thought to be approximately 30-90%. Constipation is the third most common problem in palliative care, after pain and loss of appetite. Although drug therapy is the first method that comes to mind in the treatment of constipation, as it is known, medical treatment has many side effects risks and long-term drug use causes health problems. It creates a high financial burden on the care system. The high side effects and costs of laxative drugs used in the management of constipation necessitate the use of non-pharmacological methods. Non-pharmacological methods used in the management of constipation generally include regular exercise, fluid intake, and increased consumption of fiber foods. One of them is the abdominal massage method. The number of studies on the effects of abdominal massage in the Palliative Care patient group, who frequently experience constipation, is very limited in the literature. For these reasons, the study was planned to examine the effect of abdominal massage applied to palliative care patients on constipation and quality of life.

NCT ID: NCT05734859 Completed - Clinical trials for Chronic Constipation

Drinking Effect of Electrolyzed Alkaline Reduced Water on Functional Constipation

Start date: November 30, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to investigate drinking effect of electrolyzed hydrogen-rich alkaline reduced water (EHARW) in chronic constipation patients. The main question is that drinking EHARW will improve the symptoms of chronic constipation for 4 weeks. Participants will drink EHARW (20 mL/kg of body weight/day) generated from the experimental device for 4 weeks.