Congenital Myotonia Clinical Trial
Official title:
Relations Between Fitness Status and the Severity of Myotonia in Patients With Congenital Myotonia
Investigators aimed to investigate whether training can increase fitness levels in patients with myotonia, and thereby reduce the symptom of myotonia.
Investigators aimed to investigate whether a 10-week bicycle exercise program can increase
fitness levels in patients with myotonia, and thereby reduce the symptom of myotonia in
everyday life. The effect on myotonia is assessed by a standardized myotonia scale with six
statements concerning self-rated myotonia, and a number of performance tests that
objectively describes the degree of myotonia.
The effect of the training program is assessed by an incremental test, measuring maximal
oxygen uptake, maximal heart rate and maximal workload. The muscle enzyme creatine kinase
(CK) is measured in plasma to follow muscle injury and safety during the training.
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Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment