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Clinical Trial Summary

A study to evaluate the safety and efficacy topical squaric acid dibutylester (SADBE) for the neoadjuvant treatment of congenital melanocytic nevi (CMN).


Clinical Trial Description

Patients with CMN and plans for elective surgical resection of their nevi will be enrolled in the study. Two clinically similar areas within the planned excision site will be identified, marked and treated with SADBE or the placebo solution. Following surgical resection, samples from the excised nevi will be taken and assessed for number of melanocytes. Incidence of adverse events will also be collected. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04999631
Study type Interventional
Source Massachusetts General Hospital
Contact Elena B. Hawryluk, MD, PhD
Phone 617-726-5066
Email ehawryluk@partners.org
Status Not yet recruiting
Phase Early Phase 1
Start date January 1, 2022
Completion date January 1, 2028