Pediatric Enhanced Recovery After Cardiac Surgery

Congenital Heart Disease Clinical Trial

— PERCS  

Official title:

Pediatric Enhanced Recovery After Cardiac Surgery: a Single-centre Retrospective Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05665712
• Other study ID #: Pro00104502
• Status: Completed
• Start date: November 1, 2019
• Est. completion date: August 15, 2023

Study information

• Verified date: October 2023
• Source: University of Alberta
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Identify our institution's current perioperative management strategies for pediatric cardiac surgery patients. Identify predictive factors for receiving perioperative care following P-ERACS strategies.

Compare outcomes between P-ERACS and non-P-ERACS patients

Description:

study aims to 1) assess our institution's current perioperative management strategies for pediatric cardiac surgery patients, 2) identify which patient population would be appropriate for inclusion in a pediatric ERACS (P-ERACS) program, and 3) compare the outcomes of patients whose perioperative care followed general consensus P-ERACS strategies (P-ERACS patients) and those whose perioperative care did not (non-P-ERACS patients). Results from this study will inform current efforts to establish a local P-ERACS protocol, and facilitate the initiation of a clinical trial to assess adherence to a P-ERACS pathway as well as the impact of such a pathway on patient outcomes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 483
• Est. completion date: August 15, 2023
• Est. primary completion date: August 15, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A to 18 Years

Eligibility

Inclusion Criteria:

• all pediatric patients (<18 years of age) who underwent elective cardiac surgery requiring cardiopulmonary bypass (CPB)

Exclusion Criteria:

• Emergency procedures and transplantation (heart, lung, heart and lung)

Related Conditions & MeSH terms

• Congenital Heart Disease
• ERAS
• Heart Defects, Congenital
• Heart Diseases
• Pediatric ALL

Intervention

Procedure:
• enhanced recovery
bundle of factors that have been shown to help with recovery in other surgical services such as good pain control, early ambulation, early nutrition

Locations

Country	Name	City	State
Canada	University of Alberta	Edmonton	Alberta

Sponsors (1)

Lead Sponsor	Collaborator
University of Alberta

Country where clinical trial is conducted

Canada, 

References & Publications (4)

Engelman DT, Ben Ali W, Williams JB, Perrault LP, Reddy VS, Arora RC, Roselli EE, Khoynezhad A, Gerdisch M, Levy JH, Lobdell K, Fletcher N, Kirsch M, Nelson G, Engelman RM, Gregory AJ, Boyle EM. Guidelines for Perioperative Care in Cardiac Surgery: Enhanced Recovery After Surgery Society Recommendations. JAMA Surg. 2019 Aug 1;154(8):755-766. doi: 10.1001/jamasurg.2019.1153. — View Citation

Ljungqvist O, Scott M, Fearon KC. Enhanced Recovery After Surgery: A Review. JAMA Surg. 2017 Mar 1;152(3):292-298. doi: 10.1001/jamasurg.2016.4952. — View Citation

Noss C, Prusinkiewicz C, Nelson G, Patel PA, Augoustides JG, Gregory AJ. Enhanced Recovery for Cardiac Surgery. J Cardiothorac Vasc Anesth. 2018 Dec;32(6):2760-2770. doi: 10.1053/j.jvca.2018.01.045. Epub 2018 Jan 31. — View Citation

Roy N, Parra MF, Brown ML, Sleeper LA, Nathan M, Sefton BA, Baird CW, Mistry KP, Del Nido PJ. Initial experience introducing an enhanced recovery program in congenital cardiac surgery. J Thorac Cardiovasc Surg. 2020 Nov;160(5):1313-1321.e5. doi: 10.1016/j.jtcvs.2019.10.049. Epub 2019 Oct 24. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	time to extubation	time to extubation	24 hours
Secondary	Length of stay	LOS in ICU	48 hours