Pulmonary Capillary Recruitment in Fontan Patients

Status Recruiting

Clinical Trial Summary

This study evaluates the effects of pulmonary vasodilator therapy on pulmonary capillary blood flow by measuring the functional capillary surface area (FCSA) at baseline and post nitric oxide inhalation, through the injection of 3H-benzoyl-Phe-Ala-Pro (BPAP). FCSA will be related to flow and other hemodynamic parameters in order to determine if there is capillary recruitment or distention in Fontan patients. We will also compare baseline FCSA measurements with previously studied normal subjects, to assess the difference in hemodynamic pulmonary functional parameters between these single ventricle physiology patients and normal subjects.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04292483
Study type	Observational
Source	Jewish General Hospital
Contact	David Langleben, MD
Phone	5143407531
Email	david.langleben@mcgill.ca
Status	Recruiting
Phase
Start date	June 11, 2020
Completion date	December 31, 2023

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