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Pharmacokinetics of Acetaminophen in Pediatric Patients With Congenital Heart Disease

Congenital Heart Disease Clinical Trial

Official title:
Pharmacokinetics of Acetaminophen in Pediatric Patients With Congenital Heart Disease

Clinical Trial Summary

This is a prospective study of pediatric patients with congenital heart disease, in which acetaminophen serum concentrations will be measured following a single intraoperative intravenous dose of acetaminophen. These levels will be used to develop a pharmacokinetic model. Serum concentrations will be compared between two groups of patients: (1) cyanotic patients presenting for the Fontan completion operation and (2) patients with acyanotic congenital heart disease presenting for repair via median sternotomy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04278625
Study type Observational
Source Nationwide Children's Hospital
Contact
Status Completed
Phase
Start date March 23, 2021
Completion date February 16, 2022
View Details
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