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Congenital Cataract clinical trials

View clinical trials related to Congenital Cataract.

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NCT ID: NCT05782452 Completed - Congenital Cataract Clinical Trials

Genetic Diagnosis in Congenital Cataracts

Start date: January 1, 2021
Phase:
Study type: Observational

The prediction of genetic risk in congenital cataract patients has great clinical significance. In this trial, the investigators aim to screen the causative variants from 115 unrelated bilateral congenital cataract patients enrolled consecutively, describe novel and recurrent variants, analyze the factors affecting genetic diagnostic yield, and explore potential phenotype-genotype correlation.

NCT ID: NCT05451745 Active, not recruiting - Congenital Cataract Clinical Trials

Glaucoma Following Pediatric Cataract Surgery

Start date: January 2011
Phase:
Study type: Observational

The purpose of this study is to report the incidence and related risk factors glaucoma following cataract surgery (GFCS). and to provide evidence-based evidence for the development of standardized follow-up methods or diagnosis and treatment decisions.

NCT ID: NCT05446077 Completed - Congenital Cataract Clinical Trials

Quantitatively Analysis of Fundus Structure Characteristics in Glaucoma Following Congenital Cataract Surgery

Start date: December 1, 2020
Phase:
Study type: Observational [Patient Registry]

To quantitatively analyze the fundus structure and microvascular characteristics of GFCS and non-GFCS (NGFCS) using optical coherence tomography angiography (OCTA), to explore the vascular-structural association, and to assess the diagnostic abilities of structure parameters.

NCT ID: NCT05282147 Not yet recruiting - Congenital Cataract Clinical Trials

Digital Imaging Versus Ophthalmoscopy

DIvO
Start date: June 2022
Phase: N/A
Study type: Interventional

Cataract (cloudiness of the lens) is the major cause of avoidable child blindness in the world and affects 1 in 3000 UK infants. Screening may fail to detect a cataract in an affected child (false-negative) or mistakenly suggest there is a cataract (false positive) triggering urgent unnecessary referral. Screening is currently undertaken using an ophthalmoscope into the eye to assess the reddish reflected light (red-reflex). This study aims to test if screening using a new hand-held digital imaging device (Neocam) is more accurate than the ophthalmoscope for newborn eye screening.

NCT ID: NCT05278936 Completed - Congenital Cataract Clinical Trials

New Technique in Congenital/Pediatric Cataract Surgery

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

In pediatric/congenital cataract surgery; multiple surgical interventions are performed, which needs multiple general anesthesias. Here, we describe a new technique, to end the operation in one session.

NCT ID: NCT05275764 Recruiting - Congenital Cataract Clinical Trials

Comparison of the Efficacy of Intraocular Lens Optic Capture and In-the-bag Implantation Over 1 Year in Children With Congenital Cataract

Start date: November 1, 2021
Phase:
Study type: Observational

Approximately 30 eyes with congenital cataract who underwent primary or secondary intraocular lens implantation surgery at Zhejiang Eye Hospital from March 2018 to December 2020 were enrolled. According to the implantation method of IOL, patients were devided into the optic capture group and the endocapsular group. And through the clinical parameters of postoperative best corrected visual acuity (BCVA), intraocular pressure (IOP), IOL position and whether appear visual axis opacity to compare the outcome of the 2 IOL implantation methods.

NCT ID: NCT05136209 Recruiting - Congenital Cataract Clinical Trials

Comparison of Posterior Continuous Curvilinear Capsulorhexis With or Without Anterior Vitrectomy

Start date: November 1, 2021
Phase: N/A
Study type: Interventional

Selecting the appropriate surgical approach for congenital cataracts presents challenging for ophthalmologists. This prospective, randomized controlled study aims to compare the prognosis of posterior continuous curvilinear capsulorhexis (PCCC) with or without anterior vitrectomy (A-Vit) in treating congenital cataracts.

NCT ID: NCT04976608 Recruiting - Congenital Cataract Clinical Trials

Relationship of Retinal and Visual Cortex Structure and Visual Acuity After Congenital Cataract Surgery

Start date: June 16, 2021
Phase:
Study type: Observational

To evaluate the influence of the visual acuity after congenital surgery on the retinal and visual cortex structure.

NCT ID: NCT04824963 Recruiting - Congenital Cataract Clinical Trials

Analysis of Related Factors Affecting the Secondary Implantation of Intraocular Lens in Congenital Cataract

Start date: March 27, 2021
Phase:
Study type: Observational

The ocular biometric parameters of the children with congenital cataract including preoperative pupil diameter, corneal diameter, axial length, anterior and posterior capsule size, iris adhesion. And then analysis whether the preoperative parameters were correlated with the implantation site of secondary implantation.

NCT ID: NCT04759560 Recruiting - Congenital Cataract Clinical Trials

Biometric Characteristics of the Eye With Microcornea/Microphthalmia and Congenital Cataract Before And After Cataract Extraction

Start date: July 25, 2020
Phase:
Study type: Observational

Early cataract surgery in microcornea/microphthalmia eyes is essential to prevent amblyopia and improve visual outcomes, including stereopsis. However, despite recent advances in pediatric cataract microsurgical techniques, this surgery remains challenging owing to several intraoperative difficulties attributable to the crowded anterior segment in these small, soft, and poorly developed eyes with shallow anterior chambers, and poor pupillary dilation. In this study the investigator aim to report on the changes in the anterior segment biometric characteristics after cataract extraction in eyes with microcornea/microphthalmia with congenital cataract.