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Congenital Abnormalities clinical trials

View clinical trials related to Congenital Abnormalities.

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NCT ID: NCT04636476 Completed - Congenital Anomaly Clinical Trials

One Stage Correction of Congenital Penile Curvature Complex

Al-AzharCPCC
Start date: January 2015
Phase: N/A
Study type: Interventional

To present update & experience in management of congenital penile curvature complex.

NCT ID: NCT04610437 Completed - Surgery Clinical Trials

Intramedullary Resorbable Fixation System Versus K-wire for the Treatment of Lesser Toe Deformities

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Hammertoe deformity is one of the most common deformities in the foot and is characterized by dorsiflexion of the proximal phalanx at the metatarsal-phalangeal joint and a plantarflexion of the middle phalanx at the proximal interphalangeal joint. Surgical intervention for this type of deformity is indicated when the symptoms progress and conservative treatments are not enough, that is, when we are faced with a rigid painful deformity.Arthrodesis of the proximal interphalangeal joint temporarily fixed with a Kirschner wire is the most commonly used techniques. Therefore, intramedullary fixation with a PLLA needle may be a good alternative. The use of biomaterial is gaining relevance in foot surgery, with polylactic acid being the most widely used due to its strength. Its total biodegradation requires a time of 16-24 months. No cases of foreign body reaction have been described with this type of osteosynthesis material, due to its characteristics similar to those of bone. Its only drawbacks are that it increases the complexity of the technique and that it increases the cost of the procedure. Being a flexible needle, it allows to leave a functional intraoperative claw. It maintains the functionality of the distal interphalangeal joint and carries a lower risk of infection by carrying osteosynthesis material on the outside. The purpose of the present study is to prospectively collect clinical and radiographic outcomes of operative correction of hammertoe deformity using a fixation system of intramedullary device of polylactic acid versus a kirschner wire.

NCT ID: NCT04607109 Completed - Clinical trials for Neurodevelopmental Abnormality

Long-term Neurodevelopmental Disorders of Prematurely Born Children and Parental Experience

PREMA7
Start date: November 2, 2020
Phase:
Study type: Observational

Thanks to the evolution in knowledge and technical advances in premature newborn intensive care, the survival of very premature infants is now possible. However, prognosis remain sometimes uncertain. In 2011, the Epipage 2 study showed a significant improvement as compared with the 1997 Epipage1 study with a decrease in mortality and an increase of the survival rate without severe morbidity of 14% for preterm babies born between 25 and 29 weeks and 6% for babies born between 30 and 31 weeks. However, surviving babies without initial major deficiencies, may later show problems in terms of growth, sensory - motor and/or neuro-psychologic development. This untoward evolution lead to social and family interaction disorders and school difficulties. In this context, a perinatal care network was created for each Region in France, making it possible to take care of these vulnerable children early on and all along their development. A retrospective study will evaluate 97 pre-term babies born before 33 weeks in 2012 and who are taken care of at Nancy as part of the Lorraine regional network program "Rafael" until they are 7 years old. The objective is to evaluate objectively the neurocognitive and school abilities of these children at the age of 7. At 8 years of age, a secondary measure of outcome will be the impact of the eventual neurocognitive consequences on the quality of their family life, on the behavior of the child and the parents' feelings. This way more options to improve the way they are taken care of will be available.

NCT ID: NCT04598503 Completed - Clinical trials for Congenital Anomalies

Congenital Anomalies and Risk Factors

Start date: December 1, 2017
Phase:
Study type: Observational [Patient Registry]

The aim of the study is to determine the prevalence, describe the types and risk factors of congenital anomalies among newborns admitted to Neonatal Intensive Care Unit (NICU) of Assiut University Children Hospital (AUCH). It is a prospective and a case control study was performed and screening of the newborn admitted at NICU of Assiut University Children Hospital during the period of 6 months from 1-12-2017 to the end of 5-2018 the sample was 346 newborns, 173 cases and 173 control. Data were collected using a record checklist and an interviewing questionnaire. Conclusion: The prevalence of congenital anomalies was 22.97%. The most common anomalies were gastrointestinal anomalies (GIT), musculoskeletal anomalies, multiple anomalies and circulatory system anomalies. The risk factors were consanguineous marriage, positive family history, urban areas, full-term and singleton pregnancies.

NCT ID: NCT04512118 Completed - Clinical trials for Presence of COVID-19 Compatible CT Abnormalities

CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients

Start date: March 15, 2020
Phase:
Study type: Observational

CT signs that are evocative of lung COVID-19 infections have been extensively described, whereas 18F-FDG-PET signs have not. Our current study aimed to identify specific COVID-19 18F-FDG-PET signs in patients that were (i) suspected to have a lung infection based on 18F-FDG-PET/CT recorded during the COVID-19 outbreak and (ii) whose COVID-19 diagnosis was definitely established or excluded by appropriate viral testing.

NCT ID: NCT04503759 Completed - Trauma Injury Clinical Trials

Artoss Foot and Ankle Surgery Registry

ARK
Start date: August 1, 2020
Phase:
Study type: Observational [Patient Registry]

This prospective registry was designed as an observational study to ascertain how commercially available NanoBone products are being used by surgeons performing foot and ankle surgery which involves bone grafting, as well as determining relevant patient outcomes.

NCT ID: NCT04486794 Completed - Clinical trials for Tear Trough Eyelid Deformity

Restylane® for the Treatment of Tear Trough Deformity

Start date: July 7, 2019
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness and tolerability of Restylane® for correction of tear trough deformity, using various injection techniques.

NCT ID: NCT04486599 Completed - Venous Malformation Clinical Trials

Electromagnetic Navigation During Ultrasound Guided Foam Sclerotherapy for Venous Malformations

SCLERONAV
Start date: July 15, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the feasibility of assisted electromagnetic navigation in percutaneous echo-guided sclerotherapy of slow-flow vascular malformations. Feasibility will be defined in terms of the percentage of patients for whom the procedure is successful.

NCT ID: NCT04471259 Completed - Haglund's Deformity Clinical Trials

Functional Follow-up After Endoscopic Calcaneoplasty for Haglund's Deformity

Start date: January 22, 2012
Phase:
Study type: Observational

Isokinetic muscle strength test implemented by the Biodex system is a method used for evaluating muscle function that has been applied clinically in the field of sports and rehabilitation medicine. However, information on its application on Haglund's deformity remain insufficient. Therefore, the present study is designed to examine the effectiveness of the muscle strength test using the Biodex system in evaluating the recovery of athletic capacity in patients with Haglund's deformity following endoscopic surgery.

NCT ID: NCT04468555 Completed - Hallux Valgus Clinical Trials

Hallux Valgus Manual Therapy Based on Global Postural Reeducation.

HVMT
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

Manual approach of Hallux Valgus with global postural reeducation.