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Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes — TRMC-004  

Concussion, Mild Clinical Trial

Official title:
Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes and a Comparison of the Effect of Nicotinamide Riboside Supplementation on Brain NAD+ Levels

Clinical Trial Summary

Can nicotinamide riboside (750 mg/day for 12 weeks) affect the levels of NAD+ in the brain as measured by 31P MRS?

Clinical Trial Description

Healthy collegiate athletes (football, soccer, rugby, hockey, and volleyball) will take Nicotinamide Riboside (NR) or placebo twice daily for 84 days. Pre- and post-intervention evaluations include physical assessment, blood tests for safety and toxicity monitoring, blood tests for biomarkers, neurologic testing, quality of life questionnaires, and the 31P MRI exam. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02721537
Study type Interventional
Source Mayo Clinic
Contact
Status Completed
Phase N/A
Start date September 2016
Completion date August 2022
View Details
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