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Complications clinical trials

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NCT ID: NCT00991575 Completed - Clinical trials for Diabetes Mellitus, Type 1

Long Term Vascular Changes in Type 1 Diabetes

DM09
Start date: April 1, 2009
Phase:
Study type: Observational

The main purpose of this study is to investigate progression of late complications of diabetes during the last ten years in a well characterized cohort of type 1 diabetes with a long duration of the disease, and to define factors responsible for the progression of late complications.

NCT ID: NCT00968045 Completed - Clinical trials for Coronary Artery Disease

Fibrinogen and Bleeding After Cardiac Surgery

Fibro-3
Start date: April 2009
Phase: Phase 2
Study type: Interventional

The study hypothesis is that prophylactic fibrinogen infusion reduces postoperative bleeding and transfusion requirements after coronary artery bypass surgery (CABG) in patients with endogenous fibrinogen levels in the lower normal range. 60 patients will be included in a prospective, randomized double-blind placebo-controlled single center study.

NCT ID: NCT00925912 Completed - Postoperative Pain Clinical Trials

A Trial of Closed Hemorrhoidectomy Under Local Perianal Block Versus Spinal Anesthesia

Start date: December 2006
Phase: N/A
Study type: Interventional

Hemorrhoidectomy can be carried out under several modes of anesthesia. In western country hemorrhoidectomy usually be performed under general anesthesia, however there may be the complications resulted from general anesthesia together with associated diseases in advanced age, caudal or spinal anesthesia has been used as an alternative to general anesthesia (GA) for hemorrhoid surgery but they all require a trained anesthetist and have numerous known complications. Since, anesthesiologists are not always available then local anesthesia is an alternative mode of anesthesia that surgeon can safely carry out by their own. Local anesthetic produce a loss of sensation and muscle paralysis in a circumscribed area of body by localized effect on peripheral nerve endings. The local anesthesia is able to provide fully relaxation of the anal canal which is an ideal setting for various anal surgical procedures. The results of hemorrhoid surgery under this mode of anesthesia have been demonstrated in many publications. Local anesthesia is a safe and effective technique while fewer risks and complications compared with general or spinal anesthesia. In Thailand both spinal anesthesia and local perianal block have routinely been used for various kinds of anorectal surgery. However, so far there has no any trial conducting to compare between these two techniques.

NCT ID: NCT00905229 Withdrawn - Bleeding Clinical Trials

Comparing Different Routes and Doses of Phytonadione (Vitamin K) for Reversing Warfarin Treated Patients With Hip Fracture Before Surgery

Start date: May 2009
Phase: N/A
Study type: Interventional

It is well known that femoral neck fractures carry a significant increase in patients' mortality and that surgical intervention is the preferred treatment. Any delay in operating on such patients would inevitably increase their risk of developing complications. One of the reasons for such unintentional delay would be the hypercoagulative status of patients taking warfarin. The CHEST 2008 guidelines suggest reversing warfarin with Vitamin K for patients who need urgent operation. The aim of this study is to compare different roots and doses of Vitamin K.

NCT ID: NCT00816933 Recruiting - Pain Clinical Trials

Trial on Postoperative Outcomes According to the Number of Trocar During Laparoscopic Appendectomy

Start date: January 2009
Phase: Phase 1
Study type: Interventional

Appendicitis is the most common benign inflammatory disease that requires an operation. Laparoscopic appendectomy using three trocar is generally performed, and reveals good surgical outcomes incluing less pain, early recovey, cosmetic effect et al. However, with using three trocar, there are some problems including pain around trocar insertion sites(three portions), wound infecton and scar at trocar insertion sites. For these reasons, more minimal invasive appendectomy is required, with development of laparoscopic instrument,eventually one port sppectomy is developed. So, the investigators assess post-operative Outcomes according to the Number of Trocar.

NCT ID: NCT00733434 Recruiting - Thrombosis Clinical Trials

The Use of Prostaglandin E1 in Head and Neck Microsurgery

PGE1HNM
Start date: July 2008
Phase: Phase 4
Study type: Interventional

Prostaglandin E1 (PGE1 )has been shown to have vasodilatation and anti-thrombosis effects, so it is used by some surgeons after microsurgery to keep the patency of the anastomosed small vessels. However, PGE 1 may also causes some complications, like pleural effusion or deep vein thrombosis. Therefore, it remains uncertain whether a routine use of PGE 1 after head and neck microsurgery is justified. We aim to test the hypothesis that PGE 1 increases postoperative vessel patency rate in patients undergoing head and neck microsurgery, with a comparable complication rate as the control group.

NCT ID: NCT00621491 Completed - Venous Thrombosis Clinical Trials

Prevention of Venous Thrombosis After Permanent Transvenous Leads Implantation

Start date: February 2004
Phase: N/A
Study type: Interventional

The aim of this study was to compare the safety and efficacy of warfarin versus placebo, administered for 6 months, in the prevention of thromboembolic complications after transvenous cardiac devices implantation in high-risk patients.

NCT ID: NCT00616824 Terminated - Postoperative Pain Clinical Trials

The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction

Start date: September 2007
Phase: Phase 4
Study type: Interventional

This study intends to compare postoperative outcomes of a tissue expander placement following a mastectomy with two different operative techniques. This study will be randomized and double blinded comparing the traditional placement of the tissue expander under an inferolateral serratus muscle flap to a new technique which uses an acellular dermal matrix as an inferolateral sling, instead of the muscle flap. The study we are proposing will evaluate the question of whether there is a difference between the traditional method of serratus flap and the new technique of using an acellular matrix with tissue expander placement. This will be a double blinded randomized study of thirty women in each group comparing outcomes which will include postoperative pain, complications (wound infection, hematoma, capsular contracture, etc), and patient satisfaction with the procedure.

NCT ID: NCT00564356 Recruiting - Complications Clinical Trials

The Safety of Cataract Removal by Phacoemulsification Surgery in Patients Under Anti-aggregant and Coumadin Treatment

Start date: July 2007
Phase: N/A
Study type: Interventional

To assess the risks of intra- and postoperative bleeding tendency associated with cataract surgery by phacoemulsification in patients on coumadin and antiaggregant treatments. Design: Consecutive prospective study.