Spatially Transcriptomics Reveals Molecular Signatures in CRPS

Status Recruiting

Clinical Trial Summary

This observational study aims to understand phenotype-specific molecular signatures in patients with complex regional pain syndrome (CRPS).

Clinical Trial Description

Participants who meet the diagnostic criteria for CRPS, aged 19~80 years, and agree to participate in this study will undergo a 4mm-sized skin punch biopsy in the involved limb, as well as the contralateral side (internal control). Spatial transcriptomics will be used to identify immune cell signatures and differentially regulated genes (DEGs) in the epidermis, vasculature, sweat gland, and nerve plexus of the involved ipsilateral (vs contralateral) side of the patient's skin. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05986461
Study type	Observational [Patient Registry]
Source	Seoul National University
Contact	Jee Youn Moon, MD, PhD
Phone	82-10-5299-2036
Email	jymoon0901@gmail.com
Status	Recruiting
Phase
Start date	July 18, 2023
Completion date	December 31, 2024

View Details

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