Complex Regional Pain Syndromes Clinical Trial
Official title:
The Effect of Spinal Cord Stimulation on Thermal Forward Looking InfraRed (FLIR) Imaging in Complex Regional Pain Syndrome (CRPS)
The goal of this observational study is to compare thermal camera Forward Looking InfraRed (FLIR) images before and after spinal cord stimulation to evaluate the difference in sympathetic activity of the affected limb in patients with complex regional pain syndrome (CRPS). The main questions it aims to answer are: Question 1: Can Infrared (FLIR) imaging be used to monitor the sympatholytic activity caused by Spinal Cord Stimulation (SCS) in patients with CRPS? Question 2: Is there any correlation between the quantification of sympatholytic activity produced by Spinal Cord Stimulation (SCS) and measured by FLIR imaging with the outcome measures in patients with CRPS? Outcome measures include pain (NRS), CRPS Severity Score (CSS), Quality of Life (SF-36), and neuropathic pain score (painDETECT). Participants will have an image of their feet taken perpendicularly with a 1-inch space from all four sides using a FLIR T420 or T62101 camera with 320*240 resolution. Participants will also complete questionnaires about the average pain, CRPS severity, quality of life, and neuropathic pain.
Patients with CRPS often present with sympathetic dysfunction and peripheral vasomotor disturbances. Spinal Cord Stimulation (SCS) may have a sympatholytic effect with improved microcirculation and regional blood flow. This research proposal aims to investigate the potential use of Forward Looking Infrared (FLIR) imaging to monitor whether the sympatholytic effect is enhanced by using SCS in CRPS patients. The goal of this observational study is to compare thermal camera Forward Looking InfraRed (FLIR) images before and after spinal cord stimulation to evaluate the difference in sympathetic activity of the affected limb in patients with complex regional pain syndrome (CRPS). The main questions it aims to answer are: Question 1: Can Infrared (FLIR) imaging be used to monitor the sympatholytic activity caused by Spinal Cord Stimulation (SCS) in patients with CRPS? Question 2: Is there any correlation between the quantification of sympatholytic activity produced by Spinal Cord Stimulation (SCS) and measured by FLIR imaging with the outcome measures in patients with CRPS? Outcome measures include pain (NRS), CRPS Severity Score (CSS), Quality of Life (SF-36), and neuropathic pain score (painDETECT). Participants will have an image of their feet taken perpendicularly with a 1-inch space from all four sides using a FLIR T420 or T62101 camera with 320*240 resolution. Participants will also complete questionnaires about the average pain, CRPS severity, quality of life, and neuropathic pain. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT04066933 -
Forms of Cervical Brachial Syndrome Treated With Plasma Concentrate Enriched for A2M
|
||
| Completed |
NCT04597866 -
Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up
|
||
| Completed |
NCT04060875 -
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
|
||
| Not yet recruiting |
NCT06453447 -
Prednisone for CRPS in Distal Radius Fracture
|
N/A | |
| Terminated |
NCT01954888 -
Impact of the Ultrasound-guided Approach on the Efficiency and Safety of the Stellate Ganglion Block in Chronic Pain
|
N/A | |
| Terminated |
NCT00689585 -
Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS)
|
Phase 2 | |
| Recruiting |
NCT00377468 -
Effect of Delta-9-Tetrahydrocannabinol on the Prevention of Chronic Pain in Patients With Acute CRPS (ETIC-Study)
|
Phase 2 | |
| Recruiting |
NCT05787119 -
Benefit of Augmented Reality Mirror Therapy in Addition to Conventional Management in Complex Regional Pain Syndrome of the Upper Extremity
|
N/A | |
| Recruiting |
NCT05523934 -
Retrospective Analysis of capsaïcin Patch in Complex Regional Pain Syndrome
|
||
| Recruiting |
NCT04732325 -
Sensory Testing of Multiple Forms of Spinal Cord Stimulation for Pain
|
N/A | |
| Completed |
NCT03174249 -
Exposure Therapy Combined With Cortical Interventions for CRPS-II
|
N/A | |
| Recruiting |
NCT06033456 -
Combining Stellate Ganglion and T2 and T3 Radiofrequency Ablation on Post-mastectomy Complex Regional Pain Syndrome
|
N/A | |
| Recruiting |
NCT04144972 -
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
|
N/A | |
| Completed |
NCT02490436 -
Novel Treatment Option for Neuropathic Pain
|
Phase 2 | |
| Withdrawn |
NCT03316066 -
Comparison of Volumes of Local Anesthetics on the Efficiency and Safety of Stellate Ganglion Block for CRPS of the Arm
|
N/A | |
| Recruiting |
NCT05491499 -
Assessing the Impact of Exercise Based Intensive Interdisciplinary Pain Treatment (IIPT) on Endogenous Pain Modulation in Youth With Chronic Pain Syndromes
|
||
| Completed |
NCT03291197 -
Tolerability of Suprascapular and Median Nerve Blocks for the Treatment of Shoulder-hand Syndrome
|
Phase 4 | |
| Recruiting |
NCT05034835 -
Impact of Compression Garments on Pain in Patients With Complex Regional Pain Syndrome of the Upper Limbs.
|
N/A | |
| Completed |
NCT05696587 -
Physical and Psychological Changes in CRPS Patients Undergoing Multimodal Rehabilitation
|
N/A | |
| Recruiting |
NCT02957240 -
Graded Motor Imagery for Women at Risk for Developing Type I CRPS Following Closed Treatment of Distal Radius Fractures
|
N/A |