pedCAPNETZ - Community Acquired Pneumonia (CAP) in Childhood and Adolescence

Community-acquired Pneumonia Clinical Trial

— pedCAPNETZ  

Official title:

pedCAPNETZ - Development and Detailed Characterization of a Cohort for Community Acquired Pneumonia (CAP) in Childhood and Adolescence

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04047108
• Other study ID #: pedCAPNETZ
• Status: Recruiting
• Start date: December 18, 2014
• Est. completion date: December 31, 2023

Study information

• Verified date: November 2019
• Source: Hannover Medical School
• Contact: Martin Wetzke, Dr. med
• Phone: 0511-532-3251
• Is FDA regulated: No
• Study type: Observational [Patient Registry]

Clinical Trial Summary

Establishment of a study network and patient cohort for pediatric CAP

Description:

The aim of the project is the development of a large pediatric CAP patient cohort based on the established pedCAPNETZ pilot cohort. The main objective is to improve knowledge on etiology, epidemiology, diagnosis and management of pediatric CAP in a developed country. pedCAPNETZ will enable the systematic and detailed characterization of pediatric CAP cases on an epidemiological, clinical and biological level.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1000
• Est. completion date: December 31, 2023
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 18 Years

Eligibility

Inclusion Criteria:

• age < 18

• symptoms of an acute lower respiratory tract infection with radiological confirmed pneumonia via ultrasound or chest x-ray

Exclusion Criteria:

• hospitalization for any reason within the last 28 days

• congenital or acquired immunodeficiency

• concomitant respiratory disease with impaired mucociliary clearance such as cystic fibrosis, primary ciliary dyskinesia, tracheostomy or other severe lung disease including pulmonary tuberculosis, malignancy, and cytostatic therapy during past 28 days or neutropenia (< 1000/µl) or relevant immunosuppressive treatment

Related Conditions & MeSH terms

• Community-acquired Pneumonia
• Pneumonia

Locations

Country	Name	City	State
Germany	Medizinische Hochschule Hannover	Hannover

Sponsors (1)

Lead Sponsor	Collaborator
Hannover Medical School

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of patients with pediatric community acquired pneumonia (pedCAP) across all different levels of health care	To establish a multicenter national, prospective, observational and longitudinal pedCAP database and collaborative research network	5 years
Primary	Prevalence of pedCAP and etiologies (composite outcome measures) across all different levels of health care	Etiology of pedCAP in Germany; Clinical presentation of pedCAP; Predictors of severe clinical course of pedCAP; Diagnostics employed in management of pedCAP; Microbiology and virology of pedCAP; Radiology of pedCAP; Comorbidity in patients with pedCAP; Treatment patterns of pedCAP	5 years