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Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP — NIHCAP  

Community-acquired Pneumonia Clinical Trial

Official title:
Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For Community-Acquired Pneumonia

Clinical Trial Summary

This is a prospective interventional study to assess laboratory testing which will identify the microbial cause of pneumonia. This, in turn, will allow targeted antimicrobial agent selection for patients with community acquired-pneumonia (CAP).

Hypothesis: 1) To determine if Targeted strategy is non-inferior to Empiric therapy with respect to outcome endpoints. 2) To assess the use of innovative POC tests allows targeted narrow-spectrum antimicrobial therapy. 3) To determine if Targeted strategy is superior to Empiric therapy in patients with viral pneumonia

Clinical Trial Description

The study will be conducted at five academic medical university sites with 7 hospitals. Empiric therapy is defined as selection of antibiotic therapy based on the 2007 ATS-IDSA guidelines in which broad-spectrum antibiotics are recommended, and microbial cause is uncertain ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01662258
Study type Interventional
Source University of Pittsburgh
Contact
Status Withdrawn
Phase N/A
Start date October 2012
Completion date August 2013
View Details
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