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Evaluation of ColdZyme® on Experimentally Induced Common Cold. — COLDPREVII  

Common Cold Clinical Trial

Official title:
Evaluation of ColdZyme® on Experimentally Induced Common Cold. -A Double-blind, Randomized, Placebo-controlled Study in Healthy Volunteers.

Clinical Trial Summary

This study evaluates the performance of ColdZyme® mouth spray on prevention of common cold symptoms on experimentally induced rhinovirus upper respiratory tract infection in healthy volunteers. Half of participants will receive ColdZyme® mouth spray while the other half will receive placebo.

Clinical Trial Description

88 subjects will be inoculated with rhinovirus 16 via the nasal route. The subjects will be randomized 1:1 to ColdZyme® or placebo. Treatment (6 doses per day) will be applied for 11 days from the day of inoculation. The subjects will visit the investigational clinic on 6 occasions. During these visits the subjects will leave nasal (lavage) and pharyngeal (swab) samples for quantification of virus replication. All subjects will have a diary for scoring of cold symptoms. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02479750
Study type Interventional
Source Enzymatica AB
Contact
Status Completed
Phase N/A
Start date March 23, 2016
Completion date July 25, 2016
View Details
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