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Colorectal Tumor clinical trials

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NCT ID: NCT05558436 Active, not recruiting - Colorectal Tumor Clinical Trials

Comparison of Diagnostic Sensitivity Between ctDNA Methylation and CEA in Colorectal Cancer

Start date: June 1, 2022
Phase:
Study type: Observational [Patient Registry]

This is a prospective diagnostic study. This study is to compare the performance between circulating tumor DNA (ctDNA) methylation and carcinoembryonic antigen (CEA) in detecting colorectal tumor. Firstly, based on the identification of differential ctDNA methylation biomarkers, the diagnostic model is established and the diagnostic performance was compared with that of CEA. Secondly, the stage stratification model was established preliminarily based on differential ctDNA methylation biomarkers and the performance was also compared with that of CEA.

NCT ID: NCT04013152 Active, not recruiting - Ulcerative Colitis Clinical Trials

Clinical Database of Colorectal Robotic Surgery

ROBOT CR
Start date: June 13, 2018
Phase:
Study type: Observational [Patient Registry]

Evaluation of robot Da Vinci Xi by determining its learning curve.The operating time will be defined by patient then the operating average will be calculated.

NCT ID: NCT03350945 Not yet recruiting - Colorectal Tumor Clinical Trials

Application of Carbon Nanoparticles in Laparoscopic Colorectal Surgery

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The project aims to evaluate the safety, effectiveness, accuracy and economy efficiency of the application of carbon nanoparticles for tumor localization and lymph nodes mapping in the laparoscopic coloectal surgery.

NCT ID: NCT02973490 Not yet recruiting - Colorectal Tumor Clinical Trials

Transanal Tube Drainage in Endoscopic Submucosal Dissection of the Colorectal Tumor

Start date: January 2017
Phase: N/A
Study type: Interventional

We design the clincal trial to investigate the efficacy of transanal tube drainage in colorectal ESD.

NCT ID: NCT02199912 Completed - Colorectal Tumor Clinical Trials

Study of the Relationship Between Clinical and Paraclinical Markers During Situations of Cachexia and Pre-cachexia in Patients Over 70 Years With Colorectal Surgery

ANC2
Start date: October 7, 2013
Phase: N/A
Study type: Interventional

Cachexia associated with cancer is a grave and most of the time irreversible common situation. It seems independent from the size of the tumor or from its metastatic character. The consequences for the management of the patient are major and exceed widely the frame of the nutrition. Undernutrition of patients with cancer is described by a decrease of the energy contributions and a loss of muscular and fat mass, leading to a progressive functional deficiency which can go to the cachectic state. Actually, clinical criteria are proposed allowing to characterize the state of pre-cachexia but it remain too indistinct to allow an early and efficient screening and set up effective measures of prevention of the cachexia, to avoid the loss of muscular tissue and the cast iron of the energy reserves. It is necessary to have clinical and biological markers with diagnostic aim and forecasts during the situations precedents the appearance of cachexia. The present study will allow calibrating a longitudinal study, which could confirm the value of measures made for the diagnosis of pre-cachexia.

NCT ID: NCT02084524 Recruiting - Colorectal Tumor Clinical Trials

ANC1 Study Impact of a Geriatric and Nutritional Evaluation for the Malnutrition and Malnutrition Risk Screening in Patients Over 70 Years With Colorectal Surgery.

ANC1
Start date: October 2013
Phase: N/A
Study type: Interventional

Malnutrition priori a major abdominal surgery is frequent and increases morbidity and mortality. The management of malnutrition has an impact in reducing postoperative complications. However malnutrition is rarely detected and Guidelines infrequently followed. Recovery time and nutritional evaluation in elderly patients are major criteria in their postoperative management. Identifying malnutrition or malnutrition risk is fundamental to its treatment. It is therefore unsurprising that many validated tools for nutrition risk screening and nutrition assessment exist for the clinician to use in assisting with the accurate identification, referral and treatment of patients who are malnourished or at risk of malnutrition. And nutritional management must be adapted and based on this evaluation and evolution of the general status (Guidelines Grade A). A geriatric evaluation based on a screening of preoperative malnutrition should allow a better implementation of the European Society of Parenteral and Enteral Nutrition (ESPEN) guidelines.

NCT ID: NCT00606944 Completed - Colorectal Tumor Clinical Trials

Fast-track Rehabilitation After Elective Colorectal and Small Bowel Resection

Start date: June 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to address the question of whether or not oral alimentation and ambulation exercise should be begun early in patients following laparoscopic colorectal surgery compared to the classical diet and ambulation which depends on reappearance of functional intestinal transit. Early oral alimentation following laparoscopic colorectal surgery may decrease hospital stay and facilitate earlier discharge with comparable postoperative morbidity.

NCT ID: NCT00437268 Completed - Colorectal Cancer Clinical Trials

A Study of Irinotecan Plus Cetuximab With or Without Enzastaurin in Participants With Colorectal Cancer

Start date: March 2007
Phase: Phase 2
Study type: Interventional

To see how well enzastaurin in combination with irinotecan and cetuximab works versus irinotecan and cetuximab in participants who have progressed within 3 months.

NCT ID: NCT00199862 Active, not recruiting - Colorectal Cancer Clinical Trials

Safety Study of Radio-labeled huA33 Antibody in Colorectal Cancer

Start date: February 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether our drug, 124I-huA33, can safely detect colorectal cancer.

NCT ID: NCT00114829 Recruiting - Colorectal Cancer Clinical Trials

Preoperative Assessment of Colon Tumor

Start date: July 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether a colonic tumor can be classified as malignant or benign with magnetic resonance (MR) colonography. Patients with a verified colon carcinoma or benign tumor based on diverticulitis are offered a MR colonography with intravenous (I.V.) contrast. The tumor is classified as malignant or benign by assessing the dynamic contrast uptake and morphology. The Investigator is blinded from the verified diagnosis and the MR classification is compared to the histological diagnosis.