Minimization of Surgical Site Infections for Pts Undergoing Colorectal Surgery

Colorectal Surgery Clinical Trial

Official title: Minimization of Surgical Site Infections for Pts Undergoing Colorectal Surgery

Status Completed

Clinical Trial Summary

This is a comparison, at this VA Hospital, of standard operating room management in colorectal surgery to a more rigid management using an additional five previously tested treatments to determine if this changes the rate of post operative wound infections.

Clinical Trial Description

A comparison between standard operating room:

1. use of pre-op bowel prep (Golytely or Phosphosoda,plus 3 doses of oral antibiotics(Erythromycin and Neomycin), and fleets enema the day before surgery

2. Standard anesthesia FiO2 (approx. 30-50%)during surgery

3. Standard IV fluids during surgery(greater than 200cc per hour)

4. Standard post-op O2 by mask for 2 hours

To extended operating room procedures of:

1. No po antibiotics or pre-op bowel prep other than enema prior to surgery

2. Skin warming at least 15 minutes prior to and during surgery(core temp 36C+)

3. IOBAN drapes and Plastic wound protectors used during surgery

4. Restricted IV fluids less than 200cc per hour during surgery

5. Increased FiO2 to 80% during surgery and 2 hours after by mask

Monitoring for post-op wound infections at discharge and up to 30days post-op ;

Related Conditions & MeSH terms

• Colorectal Surgery
• Communicable Diseases
• Infection
• Surgical Wound
• Surgical Wound Infection
• Surgical Wound Infections
• Wound Infection

• NCT number: NCT00953784
• Study type: Interventional
• Source: Dallas VA Medical Center
• Status: Completed
• Phase: N/A
• Start date: April 2007
• Completion date: February 2010