Colorectal Neoplasms Clinical Trial
Official title:
Development of an Endoscopic Classification Score System for Serrated Adenomas in the Colorectum
The aim of the study is to develop a score system in order to differentiate adenomatous
polyps, hyperplastic polyps and serrated adenomas on the basis of optical features.
Endoscopic images of colorectal polyps will be collected from a prospectively managed
database. Histopathological diagnoses are available for all polyps. Histopathological
diagnoses serve as gold standard in this study.
In the first phase of the study optical features of serrated adenomas are extracted from the
database. Discriminators are then defined on the basis of the extracted features. In the
second phase a test set of high quality pictures are provided to both novices and experts of
colorectal endoscopy. Participants are asked to use the above named discriminators in order
to rate pictures and to classify polyps into three classes (adenomatous polyps, hyperplastic
polyps and serrated adenomas). In the third phase of the study accuracy of optical bases
diagnoses is calculated by comparing optically derived diagnoses with histopathological
diagnoses (gold standard).
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