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Clinical Trial Summary

Primary Objective: -Evaluate the resection rate (R0/R1) in current practice for aflibercept in combination with irinotecan plus 5-fluorouracil (FOLFIRI) in patients treated for metastatic colorectal cancer (mCRC) after failure of an oxaliplatin-containing regimen Secondary Objectives: - Evaluate overall survival, progression-free survival and relapse-free survival. - Evaluate conversion rates (initially unresectable disease which became resectable after chemotherapy, with R0/R1 resection). - Evaluate histological and radiological response rates. - Evaluate rate of postoperative complications. - Evaluate safety.


Clinical Trial Description

The estimated inclusion period is 45 months. Patient follow-up is 24 months and the total study duration is 69 months. Last patient status (alive or dead) collected before database lock. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05178745
Study type Observational [Patient Registry]
Source Sanofi
Contact
Status Active, not recruiting
Phase
Start date September 7, 2016
Completion date July 31, 2022

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