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High- and Low-dose Radiotherapy Combined With PD-1 Inhibitors for MSS CRLM — HaRyPOT  

Colorectal Liver Metastases Clinical Trial

Official title:
High- and Low-dose Radiotherapy Combined With PD-1 Inhibitors for Microsatellite Stable (MSS) Colorectal Liver Metastases (CRLM)

Clinical Trial Summary

This pilot phase I trial aims to investigate the efficacy and safety of high- and low-dose radiotherapy combined with programmed cell death-1 (PD-1) inhibitors in microsatellite stable (MSS) metastatic colorectal cancer (mCRC) that have failed second-line immunotherapy or above.

Clinical Trial Description

This pilot phase I trial aims to investigate the efficacy and safety of high- and low-dose radiotherapy combined with programmed cell death-1 (PD-1) inhibitors in microsatellite stable (MSS) metastatic colorectal cancer (mCRC) that have failed second-line immunotherapy or above. 30 participants will be enrolled in this study. All will take part at Jiangsu Cancer Hospital. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06045286
Study type Interventional
Source Jiangsu Cancer Institute & Hospital
Contact Yuxuan Ding
Phone 18951590901
Email dyxoo99@163.com
Status Recruiting
Phase Phase 1
Start date September 20, 2023
Completion date December 31, 2025
View Details
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