Preoperative Hepatic Arterial Infusion Chemotherapy

Status Active, not recruiting

Clinical Trial Summary

To assess the feasibility and results of liver resection after preoperative hepatic artery infusion (HAI) chemotherapy with FUDR.

Clinical Trial Description

Between 1995 and 2004, 239 patients with isolated colorectal liver metastases received HAI chemotherapy with neoadjuvant intent. Fifty of these patients underwent subsequent curative liver resection (HAI group).

Postoperative morbidity, liver function tests, and long term outcomes were evaluated. Adverse events related to HAI chemotherapy were also evaluated. ;

Study Design

Observational Model: Defined Population, Time Perspective: Longitudinal

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00522509
Study type	Observational
Source	IRCCS San Raffaele
Contact
Status	Active, not recruiting
Phase	N/A
Start date	December 1995

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01255007` - Comparison of Primovist-enhanced MRI, Diffusion Weighted MRI and Multidetector CT of Colorectal Liver Metastases	N/A
Completed	`NCT00779272` - Impact of Preoperative Chemotherapy on Complications and Regeneration After Resection of Colorectal Liver Metastases	N/A
Active, not recruiting	`NCT00797251` - Anatomical Right Posterior Sectionectomy of the Liver by IOUS-Guided Finger Compression	N/A
Recruiting	`NCT06045286` - High- and Low-dose Radiotherapy Combined With PD-1 Inhibitors for MSS CRLM	Phase 1
Recruiting	`NCT04870879` - Colorectal Metastasis and Liver Transplantation With Organs From Deceased Donors	N/A
Completed	`NCT01799044` - Pilot-study: Non-thermal Ablation Using Irreversible Electroporation to Treat Colorectal Liver Metastases	Phase 1
Terminated	`NCT00508872` - Folfox-B Study for Patients With Colorectal Liver Metastases	Phase 2
Recruiting	`NCT05877001` - The Safety and Efficacy of HAIC+Tislelizumab+Regorafenib in Patients With Colorectal Liver Metastases	Phase 2
Completed	`NCT02082782` - Efficacy of Irreversible Electroporation (IRE) for Central Colorectal Liver Metastases	Phase 2
Completed	`NCT00942292` - The Effect of Fish Oils on Human Hepatic Colorectal Metastases	Phase 2
Recruiting	`NCT01191632` - Effect of Neoadjuvant Radiation on Tumor Infiltrating T-cells by Low Dose Radiation in Colorectal Liver Metastases	Phase 1/Phase 2
Completed	`NCT00119899` - Utility of FDG-PET Scan on the Selection of Patients for Resection of Hepatic Colorectal Metastases	Phase 3
Completed	`NCT00184834` - Quality of Life and Liver Metastases	N/A
Completed	`NCT00557557` - Safety Study of Oxaliplatin and 5-fluorouracil Followed by FUDR for Unresectable Colorectal Liver Metastases	Phase 1
Recruiting	`NCT05468593` - Patient Outcomes After Hepatic Artery Infusion Pump Placement
Completed	`NCT02615665` - Intratumoral CD3+ and NKp46+ Cells in Colorectal Liver Metastases	N/A
Terminated	`NCT01318447` - CyberKnife® for Hepatic Metastases From Colorectal Cancer	Phase 2
Completed	`NCT00885950` - Prevention of the Hepatic Sinusoidal Obstruction Syndrome by Means of Anticoagulants	N/A
Completed	`NCT02331641` - Multiple Minor Hepatectomies Versus Major or Extended Hepatectomies for Colorectal Liver Metastases.	N/A
Completed	`NCT00600522` - Alternative Surgical Policy for Central Liver Tumors	N/A