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Colorectal Disorders clinical trials

View clinical trials related to Colorectal Disorders.

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NCT ID: NCT06434727 Not yet recruiting - Clinical trials for Colorectal Disorders

Evaluating Intuitive 3D Models in Preoperative Surgical Planning for Thoracic and Colorectal Procedures.

ISI-I3DM-01
Start date: June 2024
Phase:
Study type: Observational

The Study Objective: To evaluate the clinical utility of a 3D model with 2D CT/MRI scans during simulated preoperative surgical planning of open, laparoscopic, or robotic-assisted anatomic lung resection (segmentectomy, lobectomy) or Lower Anterior Resection (LAR) procedures.

NCT ID: NCT06430931 Recruiting - Clinical trials for Colorectal Disorders

Biological OviTex Versus Synthetic Graft in Robotic Prolapse Surgery

ProTex
Start date: December 6, 2023
Phase: N/A
Study type: Interventional

This prospective study aims to assess the efficacy of the OviTex 1S permanent mesh in pelvic floor surgery in comparison with the current standard polypropylene mesh.

NCT ID: NCT06356558 Not yet recruiting - Surgery Clinical Trials

Adapting Enhanced Recovery Programs for Low Health Literacy Patients

Start date: May 2026
Phase: N/A
Study type: Interventional

Low health literacy patients are a vulnerable population at high-risk for surgical disparities including longer hospital stays, more complications, and more readmissions. This study will adapt enhanced recovery programs (ERPs) to low health literacy patients with a multilevel, health literacy-based implementation strategy (called VISACT - VISuAl aids, Coach providers in communication, and Train organizations in health literacy) to improve ERP fidelity and thereby outcomes. In the final aim of this project (Specific Aim 3), the VISACT intervention will be tested in a pilot trial. Findings from this study will lay the foundation for a multi-institutional stepped-wedge trial and establish key principles for adapting interventions to eliminate disparities.

NCT ID: NCT06342440 Recruiting - Colorectal Cancer Clinical Trials

Early Detection of Advanced Adenomas and Colorectal Cancer

AACRC
Start date: March 15, 2020
Phase:
Study type: Observational

This study aims to develop a highly sensitive, specific, and cost-effective blood assay for early detection of colorectal adenomas and cancer, using advanced machine learning and state-of-the-art biological analyses.

NCT ID: NCT06339671 Not yet recruiting - Clinical trials for Colorectal Disorders

Post-operative Complications and Smoking Habits in Colorectal Surgery

PASSAGE
Start date: April 15, 2024
Phase:
Study type: Observational [Patient Registry]

PASSAGE is a national multicenter retrospective and prospective observational cohort study in which patients who will undergo colorectal surgery will be enrolled.

NCT ID: NCT06309368 Recruiting - Clinical trials for Surgical Site Infection

Ostomy Primary Closure With 0.1% Betaine/0.1% Polyhexanide Wound Irrigation Compared to Pursestring Closure

Start date: March 14, 2024
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare two types of closure in patients with ostomies that are ready for closure. The main questions it aims to answer are: 1. Surgical site infection rates 2. Patient quality of life 3. Time to wound healing Participants will undergo either complete ostomy wound closure after washing out the wound with Prontosan, or their ostomy wound will be closed using the Pursestring method, where the wound will be left partially open and allowed to heal from the inside out. Researchers will compare these two groups' outcomes (questions to be answered) as listed above.

NCT ID: NCT06008834 Not yet recruiting - Surgery Clinical Trials

First-day Discharge Enhanced Recovery After Surgery Protocol for Minimal Invasive Colorectal Surgery

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The enhanced recovery after surgery (ERAS) protocols are multimodal perioperative care pathways designed to achieve early recovery after surgical procedures by maintaining preoperative organ function and reducing the profound stress response following surgery. This type of approach has led to an earlier hospital discharge of patients with a low rate of postoperative complications. Purpose: the aim of this study is to evaluate an ERAS protocol with fist-day hospital discharge and domiciliary follow-up for minimal invasive colectomy. Method: unicenter pilot study of patients with indication of minimally invasive right colectomy or sigmidectomy who will follow an ERAS protocol according to international guidelines and will be discharged the first day of surgery with a domiciliary follow-up. Hospital readmission is considered as the primary outcome. A total sample of 40 cases is considered, with 20 right colectomies and 20 sigmoidectomies. An independent analysis of both techniques will be performed.

NCT ID: NCT05994326 Completed - Clinical trials for Colorectal Disorders

Perioperative Care and Short-term Outcomes of Colorectal Surgery in Addis Abeba

Start date: September 12, 2022
Phase:
Study type: Observational

Observational cohort study of adult patients undergoing colorectal surgery at Tikur Anbessa Specialized Hospital in Addis Abeba for 3 months.

NCT ID: NCT05773248 Completed - Colorectal Cancer Clinical Trials

ERAS in Colorectal Surgery: Benefits of Late Adoption

Start date: March 13, 2023
Phase:
Study type: Observational [Patient Registry]

The aim of this single-center retrospective cohort study is to explore the effect of late adaptation of an ERAS protocol in a high-volume colorectal surgical unit. The primary endpoint is the surgical outcome measured by early postoperative complications, defined by the comprehensive complications index. Secondary endpoints include amongst others LOS (length of stay), cost analysis, short-term follow-up in the ERAS group.

NCT ID: NCT05726136 Recruiting - Colorectal Cancer Clinical Trials

Fluid Challenge and Plasma Volume, During Surgery

FC-VE
Start date: October 23, 2023
Phase: Phase 4
Study type: Interventional

A short bolus infusion of fluid, called "fluid challenge" is commonly recommended for fluid treatment during longer surgery. However a prolonged increase of the blood volume is a prerequisite to recommend the technique. The purpose with the study is to examine the plasma expanding effect of three different fluid challenge strategies (acetated Ringers 4 ml/kg body weight, albumin 5% 4 ml/kg body weight or albumin 20% 1 ml/kg body weight), using hemoglobin as a dilution indicator.