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Recombinant Vaccinia Virus Administered Intravenously in Patients With Metastatic, Refractory Colorectal Carcinoma

Colorectal Carcinoma Clinical Trial

Official title:
A Phase 1/2a Dose-escalation Study of JX 594 Administered by Multiple Intravenous (IV) Infusions Alone and in Combination With Irinotecan in Patients With Metastatic, Refractory Colorectal Carcinoma.

Clinical Trial Summary

The purpose of this study is to evaluate the safety, tolerability, and efficacy of JX-594 (Pexa-Vec) administered intravenously either alone or in combination with Irinotecan in colorectal carcinoma patients who are refractory to or intolerant to standard therapy.

Clinical Trial Description

This was a Phase 1/2a, open-label, dose-escalation study in patients with advanced colorectal cancer (CRC) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01394939
Study type Interventional
Source SillaJen, Inc.
Contact
Status Completed
Phase Phase 1/Phase 2
Start date January 2012
Completion date October 2015
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