A Cross-sectional Survey of Colorectal Cancer Patients in Different Age Groups

Colorectal Cancer Clinical Trial

Official title:

A Cross-sectional Survey of Symptomatic Characteristics, Family History and Pathologic Features of Colorectal Cancer Patients in Different Age Groups

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06145230
• Other study ID #: 2ndHarbinMUSUV
• Status: Recruiting
• Start date: December 12, 2023
• Est. completion date: December 1, 2024

Study information

• Verified date: January 2024
• Source: The Second Affiliated Hospital of Harbin Medical University
• Contact: Yuliuming Wang, Dr.
• Phone: +86-15765191796
• Email: wylm3141[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

Description:

Colorectal cancer is one of the common and highly prevalent malignant tumors of the gastrointestinal system. Previous studies have found that there may be some differences in disease characteristics and prognosis of colorectal cancer patients at different ages, such as patients with early-onset colorectal cancer (age <50 years) tend to have a worse prognosis than patients with late-onset colorectal cancer (age ≥50 years). However, existing studies on the characteristics of colorectal cancer patients at different ages are not well studied to answer the differences between these patients and develop targeted diagnostic and treatment strategies. Cross-sectional survey research, which uses survey research to collect data on a characteristic group over a certain period of time and statistically analyzes the data to obtain the characteristics of a certain disease or a certain treatment strategy, is a more mature approach that is particularly suitable for the questions that need to be answered in this study. Investigators found that no similar studies have been registered and conducted by searching the official websites of the China Clinical Research Registry and Clinical Trial, and there is a lack of research data on the Chinese population. Therefore, investigators believe there is an urgent need for a cross-sectional survey to study the symptomatic characteristics, family history, and pathologic features of colorectal cancer patients. This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 430
• Est. completion date: December 1, 2024
• Est. primary completion date: October 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Adults aged 18 years and older with a pathologic diagnosis of colorectal cancer;

2. Undergoing surgical treatment of the primary lesion;

3. Voluntary participation of patients.

Exclusion Criteria:

1. Do not agree to participate in the survey or withdraw informed consent

2. Patients did not receive surgical treatment or did not undergo pathologic examination

Related Conditions & MeSH terms

• Age Problem
• Colorectal Cancer
• Colorectal Neoplasms

Locations

Country	Name	City	State
China	the 2nd Affiliated Hospital of Harbin Medical University	Harbin	Heilongjiang

Sponsors (1)

Lead Sponsor	Collaborator
Wang Guiyu

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Characteristics of clinical symptoms	Comparison of the characteristics of clinical symptoms in patients of different ages;	2023.12-2024.10
Primary	Family history	Comparison of the probability of having a family history in patients of different age stages;	2023.12-2024.10
Primary	Pathological characteristics	Comparison of pathological characteristics of patients at different age stages;	2023.12-2024.10
Secondary	Risk factors	Analysis of risk factors for stage progression in colorectal cancer patients	2024.09-2024.10