Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis

Colorectal Cancer Clinical Trial

Official title:

Investigation of Preoperative Frailty in Elderly Patients With Colorectal Cancer and Correlation Between Preoperative Frailty and Early Postoperative Prognosis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05915637
• Other study ID #: KLLY-2021-025
• Status: Completed
• Start date: September 1, 2021
• Est. completion date: November 1, 2022

Study information

• Verified date: June 2023
• Source: Zunyi Medical College
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

To investigate and analyze the status of preoperative frailty and its influencing factors in elderly patients with colorectal cancer using FRALL scale and other related scales, and to explore the correlation between preoperative frailty and early prognosis in elderly patients with colorectal cancer, so as to attract the attention of medical staff to preoperative frailty in this population and provide a preliminary research basis for the study of frailty intervention in these patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 336
• Est. completion date: November 1, 2022
• Est. primary completion date: November 1, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

1. age =60 years old;

2. Colorectal cancer was diagnosed according to the Chinese Guidelines for Diagnosis and Treatment of Colorectal Cancer (2020 edition) and planned to undergo elective laparoscopic radical resection of colorectal cancer;

3. able to complete physical assessment without communication barriers;

4. voluntarily participated in this study after informed consent.

Exclusion Criteria:

1. taking antidepressants, levodopa, donepezil hydrochloride and other drugs;

2. patients with preoperative colorectal cancer surgery or neoadjuvant therapy;

3. patients with TNM stage ?;

4. complicated with other malignant tumors except primary skin cancer or melanoma.

Related Conditions & MeSH terms

• Colorectal Cancer
• Colorectal Neoplasms
• Frailty

Locations

Country	Name	City	State
China	Yongmei Zhang	Zunyi	Guizhou

Sponsors (1)

Lead Sponsor	Collaborator
Zunyi Medical College

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Fatigue Assessment	Status of frailty will be assessed by FRALL Scale	7 days