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Clinical Trial Summary

This is a 3-year pragmatic, randomized clinical trial among average-risk patients at diverse primary care practices who are overdue for colorectal (CRC) screening. This project aims to evaluate the effect of a centralized program that includes direct outreach to patients and visit-based, clinician directed nudges facilitated by the electronic health record (EHR) with follow-up text messaging on the uptake of CRC screening. The primary outcome is CRC screening completion at 3 years. Through surveys and qualitative interviews, we will explore patient and clinician factors impacting the experience and effectiveness of the intervention.


Clinical Trial Description

Despite effective strategies for prevention, early detection, and treatment, colorectal cancer (CRC) remains the second leading cause of cancer death in the United States (US). While there have been considerable policy and system-level efforts to increase CRC screening rates, uptake remains well below national goals of 80% participation. Members of racial and ethnic minorities are even further behind. Approaches to increase population-based screening can consider [1] how screening is encouraged by targeting the clinicians who typically order or recommend the procedure or the patient who completes it; and [2] the kind of screening offered (e.g., colonoscopy or fecal immunochemical testing [FIT]). This project simultaneously tests interventions along both of these dimensions. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05693649
Study type Interventional
Source Abramson Cancer Center of the University of Pennsylvania
Contact Catherine Reitz, MPH
Phone 561-302-7893
Email catherine.reitz@pennmedicine.upenn.edu
Status Not yet recruiting
Phase N/A
Start date February 2023
Completion date December 2026

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