Effect of Implementation of Enhanced Recovery After Surgery on 3-year Survival After Colorectal Surgery for Cancer

Colorectal Cancer Clinical Trial

— RACCOR  

Official title:

Effect of Implementation of Enhanced Recovery After Surgery (ERAS) Protocol on 3-year Survival After Colorectal Surgery for Cancer - a Retrospective Cohort of 1001 Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05002855
• Other study ID #: 2021
• Status: Completed
• Start date: January 20, 2021
• Est. completion date: June 30, 2021

Study information

• Verified date: September 2021
• Source: University Hospital, Grenoble
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Several recent studies have shown that the Enhanced Recovery After Surgery (ERAS) protocol reduces morbidity and mortality and shortens the length of stay compared to conventional recovery strategy (pre-ERAS). The aim of this study was to evaluate the effect of the implementation of this protocol on 3-year overall survival and postoperative outcome in patients undergoing colorectal resection for cancer.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1001
• Est. completion date: June 30, 2021
• Est. primary completion date: May 30, 2021
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Aadult patients, who had undergone resection for colorectal cancer or a precancerous lesion and were cared for using the ERAS protocol or received conventional care (pre-ERAS).

• Informed patients

Exclusion Criteria:

• Patients presenting or developing peritoneal cancer,

• Patients having resection for palliative reasons,

• Patients those under curatorship or tutelage

• Opposed patients

Related Conditions & MeSH terms

• Colorectal Cancer
• Colorectal Neoplasms

Intervention

Other:
• Enhanced Recovery After Surgery (ERAS)
Multidisciplinary approach to perioperative care.

Locations

Country	Name	City	State
France	Jean-Luc Faucheron	Grenoble

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Grenoble

Country where clinical trial is conducted

France, 

References & Publications (8)

Alfonsi P, Slim K, Chauvin M, Mariani P, Faucheron JL, Fletcher D; le groupe de travail de la Société française d'anesthésie et réanimation (Sfar) et de la Société française de chirurgie digestive (SFCD). [Guidelines for enhanced recovery after elective c — View Citation

Carrier G, Cotte E, Beyer-Berjot L, Faucheron JL, Joris J, Slim K; Groupe Francophone de Réhabilitation Améliorée après Chirurgie (GRACE). Post-discharge follow-up using text messaging within an enhanced recovery program after colorectal surgery. J Visc S — View Citation

Faucheron JL, Trilling B, Sage PY. Ambulatory colectomy: fast-track management pushed to its limits? Tech Coloproctol. 2018 Oct;22(10):741-742. doi: 10.1007/s10151-018-1871-5. Epub 2018 Nov 9. Review. — View Citation

Faujour V, Slim K, Corond P. [The future, in France, of enhanced recovery after surgery seen from the economical perspective]. Presse Med. 2015 Jan;44(1):e23-31. doi: 10.1016/j.lpm.2014.07.021. Epub 2014 Dec 22. French. — View Citation

Gignoux B, Gosgnach M, Lanz T, Vulliez A, Blanchet MC, Frering V, Faucheron JL, Chasserant P. Short-term Outcomes of Ambulatory Colectomy for 157 Consecutive Patients. Ann Surg. 2019 Aug;270(2):317-321. doi: 10.1097/SLA.0000000000002800. — View Citation

Launay-Savary MV, Mathonnet M, Theissen A, Ostermann S, Raynaud-Simon A, Slim K; GRACE (Groupe francophone de Réhabilitation Améliorée après Chirurgie). Are enhanced recovery programs in colorectal surgery feasible and useful in the elderly? A systematic — View Citation

Slim K, Delaunay L, Joris J, Léonard D, Raspado O, Chambrier C, Ostermann S; Le Groupe francophone de réhabilitation améliorée après chirurgie (GRACE). How to implement an enhanced recovery program? Proposals from the Francophone Group for enhanced recove — View Citation

Trilling B, Sage PY, Faucheron JL. What is fast track multimodal management of colorectal cancer surgery in real life? Tech Coloproctol. 2018 May;22(5):401-402. doi: 10.1007/s10151-018-1799-9. Epub 2018 Jun 1. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Evaluate the effect of the implementation of this protocol on 3-year overall survival.	3-year overall survival rate	3 years