Application of MR-PET in Colorectal Cancer

Colorectal Cancer Clinical Trial

Official title:

Application of MR-PET in Colorectal Cancer

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02553031
• Other study ID #: 201403082MIND
• Status: Recruiting
• Phase: N/A
• First received: September 10, 2015
• Last updated: May 14, 2017
• Start date: July 2014
• Est. completion date: May 2018

Study information

• Verified date: May 2017
• Source: National Taiwan University Hospital
• Contact: Ting-Fang Shih, MD
• Phone: +886-2-23123456
• Email: ttfshih[@]ntu.edu.tw
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study will explore the potential value in proper therapeutic decision and clinical outcome prediction by using integrated MR-PET system and advanced MR techniques in patients with colorectal cancer.

Description:

This research expect that the image techniques and experience in this cancer group may be valuable and helpful for others. With advantage of MR-PET in better soft tissue delineation/functional information and less radiation dose than PET-CT, the ultimate goal in both research and clinical application is to establish new diagnostic standard and management guideline by MR-PET, which can further improve clinical outcome and disease prognosis in patients colorectal cancer.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 100
• Est. completion date: May 2018
• Est. primary completion date: December 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 90 Years

Eligibility

Inclusion Criteria:

1. Group 1: Patients with newly diagnosed colorectal cancers

2. Group 2: Patients with suspicious recurrent colorectal cancers

Exclusion Criteria:

1. Age <20 or >90 years old

2. Contraindication for MRI: claustrophobia or MR non-compatible devices

3. Contraindication for MR contrast medium: severe adverse reaction or impaired renal function (Cre > 2.0)

4. History of other malignancy

5. Prior arthroplasty of hip (may cause artifacts on MRI)

6. Pregnancy

Related Conditions & MeSH terms

• Colorectal Cancer
• Colorectal Neoplasms

Intervention

Device:
• The imaging biomarkers determined by MR-PET
This study will explore the potential value in proper therapeutic decision and clinical outcome prediction by using integrated MR-PET system and advanced MR techniques in patients with colorectal cancer.

Locations

Country	Name	City	State
Taiwan	National Taiwan University Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
National Taiwan University Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The recurrence rate at 1 year after surgery		1 year
Secondary	The overall survival at 1 year after surgery		1 year