Effect of Norwegian Food Based Dietary Guidelines on Chronic Diseases in

Status Active, not recruiting

Clinical Trial Summary

The current study is designed to gain a better understanding of the role of a healthy diet aimed at dampening inflammation and oxidative stress on long-term disease outcomes and survival in colorectal cancer patients. Since previous research on the role of diet for colorectal cancer survivors is limited, the study may be of great importance for this cancer population.

Clinical Trial Description

Men and women aged 50-80 years diagnosed with primary invasive colorectal cancer (Stage I-III) are invited to this randomized controlled, parallel two-arm trial 2-9 months after curative surgery. The intervention group (n = 250) receives an intensive dietary intervention lasting for 12 months and a subsequent maintenance intervention for 14 years. The control group (n = 250) receives no dietary intervention other than standard clinical care. Both groups are offered equal general advice of physical activity. Patients are followed-up at 6 months and 1, 3, 5, 7, 10 and 15 years after baseline. The study center is located at the Department of Nutrition, University of Oslo, and patients are recruited from two hospitals within the South-Eastern Norway Regional Health Authority. Primary outcomes are disease-free survival and overall survival. Secondary outcomes are time to recurrence, cardiovascular disease-free survival, compliance to the dietary recommendations and the effects of the intervention on new comorbidities, intermediate biomarkers, nutrition status, physical activity, physical function and quality of life. ;

Study Design

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Clinical Trial Details

NCT number	NCT01570010
Study type	Interventional
Source	University of Oslo
Contact
Status	Active, not recruiting
Phase	N/A
Start date	March 1, 2012
Completion date	December 31, 2040

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Effect of Norwegian Food Based Dietary Guidelines on Chronic Diseases in CRC Survivors — CRC-NORDIET

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms