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NCT00410618 Clinical Trial

Neurological Effects of Chemotherapy and Radiation Therapy in Patients With Colon Cancer

Colorectal Cancer Clinical Trial

Official title:
Neurological Effects of Chemotherapy and Radiation Treatment: Colon Cancer

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00410618
Other study ID # HSCB0213
Secondary ID P50CA095060P30CA
Status Completed
Phase
First received
Last updated
Start date April 2003
Est. completion date August 2006

Study information
Verified date August 2012
Source University of Arizona
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

RATIONALE: Learning about the long-term effects of chemotherapy and radiation therapy on brain function may help doctors plan cancer treatments.

PURPOSE: This clinical trial is looking at the neurological effects of chemotherapy and radiation therapy in patients with colon cancer.

Description:

OBJECTIVES:

Primary

- Identify the nature and long-term ramifications of CNS injury as a result of cancer treatment in patients with colon cancer.

Secondary

- Analyze differences in cognitive measures and MRI data in these patients.

- Correlate MRI measures with cognitive performance in these patients.

OUTLINE: Patients undergo cognitive performance assessment and MRI.

PROJECTED ACCRUAL: A total of 42 patients will be accrued for this study.

Recruitment information / eligibility
Status Completed
Enrollment 42
Est. completion date August 2006
Est. primary completion date August 2006
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility DISEASE CHARACTERISTICS:

- Diagnosis of colon cancer

- Received chemotherapy and radiotherapy for colon cancer

PATIENT CHARACTERISTICS:

- Not specified

PRIOR CONCURRENT THERAPY:

- See Disease Characteristics

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• cognitive assessment

• magnetic resonance imaging

• management of therapy complications

Locations
Country Name City State
United States Arizona Cancer Center at University of Arizona Health Sciences Center Tucson Arizona

Sponsors (2)
Lead Sponsor Collaborator
University of Arizona National Cancer Institute (NCI)

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Nature and long-term ramifications of CNS injury as a result of cancer treatment
Secondary Differences in cognitive measures and MRI data
Secondary Relationship between MRI measures and cognitive performance
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