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NCT00388206 Clinical Trial

A Study of Avastin in Combination With Chemotherapy for Treatment of Colorectal Cancer and Non-Small Cell Lung Cancer (ARIES)

Colorectal Cancer Clinical Trial

— ARIES  

Official title:
An Observational Study of Avastin (Bevacizumab) in Combination With Chemotherapy for Treatment of Metastatic or Locally Advanced and Unresectable Colorectal Cancer and Locally Advanced or Metastatic Non-Small Cell Lung Cancer (Excluding Predominant Squamous Cell Histology)

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00388206
Other study ID # AVF3991n
Secondary ID
Status Completed
Phase
First received
Last updated
Start date November 2006
Est. completion date March 2012

Study information
Verified date December 2022
Source Genentech, Inc.
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This is an observational study designed to follow patients with metastatic or locally advanced and unresectable CRC or locally advanced or metastatic NSCLC (excluding predominant squamous histology) who are receiving Avastin in combination with first-line chemotherapy. Second-line metastatic CRC patients are also eligible. Patients who started their Avastin containing therapy <4 months prior to enrollment are eligible.

Recruitment information / eligibility
Status Completed
Enrollment 3998
Est. completion date March 2012
Est. primary completion date March 2012
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: - Signed Informed Consent Form - Metastatic or locally advanced and unresectable CRC or locally advanced or metastatic NSCLC (excluding predominant squamous histology) - Eligible for Avastin as a component of intended therapy - First-line chemotherapy (or second-line chemotherapy for CRC) plus Avastin initiated = 4 months prior to study enrollment Exclusion Criteria: - Any medical condition, including mental illness or substance abuse, deemed by the investigator to be likely to interfere with a patient's ability to provide informed consent or comply with the treatment and follow-up, as specified by the investigator - Enrollment in a blinded, placebo-controlled bevacizumab trial

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Genentech, Inc.
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