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Rectal Reconstruction in Treating Patients Who Are Undergoing Surgery for Rectal Cancer

Colorectal Cancer Clinical Trial

Official title:
Clinical Function After Total Mesorectal Excision and Rectal Replacement. A Prospective Randomized Trial Comparing Side-to-End Anastomosis, Colon-J-Pouch and Straight Coloanal Anastomosis

Clinical Trial Summary

RATIONALE: Rectal reconstruction after surgery to treat rectal cancer may help patients keep some of their bowel function. It is not yet known which method of rectal reconstruction is most effective after surgery.

PURPOSE: This randomized phase III trial is studying three different methods of rectal reconstruction to compare how well they work in treating patients who are undergoing surgery for rectal cancer.

Clinical Trial Description

This is a randomized, multicenter study. Patients are stratified according to participating center, gender, distance of the distal tumor margin from the dentate line (> 5 cm vs ≤ 5 cm), age (< 70 vs ≥ 70), neoadjuvant chemoradiotherapy (yes vs no), and distant metastasis (M0 vs M1). Patients are randomized to 1 of 3 treatment arms. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00238381
Study type Interventional
Source Swiss Group for Clinical Cancer Research
Contact
Status Completed
Phase Phase 3
Start date July 2005
Completion date August 2016
View Details
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